Studying the Enteric Microbiome in Inflammatory Bowel Diseases: Getting through the Growing Pains and Moving Forward.

Studying the Enteric Microbiome in Inflammatory Bowel Diseases: Getting through the Growing Pains and Moving Forward.
复制标题

DOI:
10.3389/fmicb.2011.00144
复制
发表时间:
2011
影响因子:
5.2
通讯作者:
Chang EB
Chang EB
中科院分区:
生物学2区
文献类型:
--
作者:
Young VB;Kahn SA;Schmidt TM;Chang EB

文献摘要

参考文献

被引文献

相似文献

在这篇评论中,我们将回顾一些旨在了解肠道微生物群在炎症性肠病因果关系中的作用的早期努力。通过检查这些研究,并借鉴我们自己在临床胃肠病学和微生物生态学之间架起桥梁的经验,作为 NIH 资助的人类微生物组项目(Turnbaugh 等人)的一部分,我们希望帮助确定一些阻碍这些初步努力的“成长的烦恼”。我们真诚地希望,这次讨论将通过确定当前的挑战和局限性并提出克服这些障碍的策略来帮助推进该领域的未来努力。
In this commentary, we will review some of the early efforts aimed at understanding the role of the enteric microbiota in the causality of inflammatory bowel diseases. By examining these studies and drawing on our own experiences bridging clinical gastroenterology and microbial ecology as part of the NIH-funded Human Microbiome Project (Turnbaugh et al.,), we hope to help define some of the “growing pains” that have hampered these initial efforts. It is our sincere hope that this discussion will help advance future efforts in this area by identifying current challenges and limitations and by suggesting strategies to overcome these obstacles.
DOI: 10.1002/ibd.20278
发表时间: 2008-01-01
影响因子: 4.9
作者:
Ferrante, Marc;Declerck, Sarah;D'Hoore, Andre
通讯作者: D'Hoore, Andre
DOI: 10.1097/01.mib.0000159662.62651.06
发表时间: 2005-05-01
影响因子: 4.9
作者:
Lepage, P;Seksik, P;Doré, J
通讯作者: Doré, J
DOI: 10.1126/science.1124234
发表时间: 2006-06-02
期刊: SCIENCE
影响因子: 56.9
作者:
Gill, Steven R.;Pop, Mihai;Nelson, Karen E.
通讯作者: Nelson, Karen E.
DOI: 10.1186/gm228
发表时间: 2011-03-04
期刊: Genome medicine
影响因子: 12.3
作者:
Kinross JM;Darzi AW;Nicholson JK
通讯作者: Nicholson JK
DOI: 10.1371/journal.pone.0002836
发表时间: 2008-07-30
期刊: PLOS ONE
影响因子: 3.7
作者:
Andersson, Anders F.;Lindberg, Mathilda;Jakobsson, Hedvig;Backhed, Fredrik;Nyren, Pal;Engstrand, Lars
通讯作者: Engstrand, Lars