Socioeconomic status, health behavior, and leukocyte telomere length in the National Health and Nutrition Examination Survey, 1999-2002.
Socioeconomic status, health behavior, and leukocyte telomere length in the National Health and Nutrition Examination Survey, 1999-2002.
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DOI：
10.1016/j.socscimed.2013.02.023
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发表时间：
2013-05
影响因子：
5.4
通讯作者：
Epel, Elissa S.
中科院分区：
文献类型：
--
作者：
Needham, Belinda L.;Adler, Nancy;Gregorich, Steven;Rehkopf, David;Lin, Jue;Blackburn, Elizabeth H.;Epel, Elissa S.
本研究的目的是检查社会经济地位（SES）和白细胞端粒长度（LTL）之间的关联-一种与压力生活环境有关的细胞衰老标志物-在20-84岁的美国成年人中具有全国代表性，社会经济和种族多样性。利用1999-2002年国家健康和营养调查（NHANES）的数据，我们发现，完成高中教育以下的受访者的端粒明显短于大学毕业的受访者。收入与LTL无关。非洲裔美国人的端粒明显长于白人，但在教育和端粒长度之间的关联方面没有显着的种族/民族差异。最后，我们发现，教育和LTL之间的关联是部分介导的吸烟和体重指数，但不是由饮酒或久坐行为。
The purpose of this study was to examine the association between socioeconomic status (SES) and leukocyte telomere length (LTL) – a marker of cell aging that has been linked to stressful life circumstances – in a nationally representative, socioeconomically and ethnically diverse sample of US adults aged 20–84. Using data from the National Health and Nutrition Examination Survey (NHANES), 1999–2002, we found that respondents who completed less than a high school education had significantly shorter telomeres than those who graduated from college. Income was not associated with LTL. African-Americans had significantly longer telomeres than whites, but there were no significant racial/ethnic differences in the association between education and telomere length. Finally, we found that the association between education and LTL was partially mediated by smoking and body mass index but not by drinking or sedentary behavior.
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影响因子：
7.6
作者：
BARON, RM;KENNY, DA
通讯作者：
KENNY, DA
DOI：
10.1038/nrg3246
发表时间：
2012-10
期刊：
Nature reviews. Genetics
影响因子：
--
作者：
通讯作者：
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影响因子：
7.8
作者：
Bakaysa, Stephanie L.;Mucci, Lorelei A.;Pedersen, Nancy L.
通讯作者：
Pedersen, Nancy L.
影响因子：
15.1
作者：
Choi, Jenny;Fauce, Steven R.;Effros, Rita B.
通讯作者：
Effros, Rita B.
健康，衰老和身体成分研究中的教育程度和末期端粒长度。
影响因子：
15.1
作者：
Adler, Nancy;Pantell, Matthew S.;O'Donovan, Aoife;Blackburn, Elizabeth;Cawthon, Richard;Koster, Annemarie;Opresko, Patricia;Newman, Anne;Harris, Tamara B.;Epel, Elissa
通讯作者：
Epel, Elissa