Simultaneous determination of three 5-nitroimidazoles in foodstuffs by differential pulse voltammetry and chemometrics
Simultaneous determination of three 5-nitroimidazoles in foodstuffs by differential pulse voltammetry and chemometrics
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差示脉冲伏安法和化学计量学同时测定食品中的三种5-硝基咪唑
DOI：
10.1016/j.cclet.2010.12.014
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发表时间：
2011-05
影响因子：
9.1
通讯作者：
Kokot, Serge
中科院分区：
文献类型：
--
作者：
Gui, Yi;Ni, Yong Nian;Kokot, Serge
研究了3种5-硝基咪唑类化合物甲硝唑、替硝唑和奥硝唑的伏安行为，建立了在pH 8.95缓冲溶液中，在悬汞电极(HMDE)上用差示脉冲伏安法同时测定这些化合物的方法。这些化合物的峰电位分别为−692、−640和−652 mV。由于它们的伏安峰严重重叠，在没有预分离的情况下很难单独从混合物中分离出来，因此采用化学计量学的方法来解析重叠的伏安图并对混合物进行定量。方法成功地用于牛奶和蜂蜜中3种5-硝基咪唑的测定。
The voltammetric behaviour of three 5-nitroimidazoles, metronidazole, tinidazole and ornidazole, was investigated, and a method was developed for the simultaneous determination of these compounds, based on their reduction at a hanging mercury drop electrode (HMDE) in pH 8.95 buffer with differential pulse voltammetric (DPV) approach. Well defined voltammetric waves with peak potentials of −692, −640 and −652mV were observed for these compounds, respectively. It is difficult to determine them individually from their mixtures without preseparation, for their voltammetric peaks overlapped seriously, so the chemometrics were used to resolve the overlapped voltammogram and quantify the mixtures. The proposed method was successfully applied to the determination of three 5-nitroimidazoles in milk and honey samples.
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DOI：
10.1016/j.colsurfa.2008.11.054
发表时间：
2009-04
期刊：
Colloids and Surfaces A: Physicochemical and Engineering Aspects
影响因子：
--
作者：
R. Jain;R. Mishra;A. Dwivedi
通讯作者：
R. Jain;R. Mishra;A. Dwivedi
DOI：
10.1016/0021-9673(96)00101-x
发表时间：
1996-06
期刊：
Journal of chromatography. A
影响因子：
--
作者：
M. Gaugain;J. Abjean
通讯作者：
M. Gaugain;J. Abjean
DOI：
10.1016/j.chroma.2008.08.055
发表时间：
2008-10
期刊：
Journal of chromatography. A
影响因子：
--
作者：
X. Xia;Xiaowei Li;Suxia Zhang;S. Ding;Haiyang Jiang;Jiancheng Li;Jianzhong Shen
通讯作者：
X. Xia;Xiaowei Li;Suxia Zhang;S. Ding;Haiyang Jiang;Jiancheng Li;Jianzhong Shen
影响因子：
6.1
作者：
Lu, SF;Wu, KB;Hu, SS
通讯作者：
Hu, SS
影响因子：
6.2
作者：
X. Xia;Xiaowei Li;S. Ding;Suxia Zhang;Haiyang Jiang;Jiancheng Li;Jianzhong Shen
通讯作者：
X. Xia;Xiaowei Li;S. Ding;Suxia Zhang;Haiyang Jiang;Jiancheng Li;Jianzhong Shen