Unlocking capacities of genomics for the COVID-19 response and future pandemics.
Unlocking capacities of genomics for the COVID-19 response and future pandemics.
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DOI：
10.1038/s41592-022-01444-z
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发表时间：
2022-04
期刊：
影响因子：
48
通讯作者：
Mangul, Serghei
中科院分区：
文献类型：
--
作者：
Knyazev, Sergey;Chhugani, Karishma;Sarwal, Varuni;Ayyala, Ram;Singh, Harman;Karthikeyan, Smruthi;Deshpande, Dhrithi;Baykal, Pelin Icer;Comarova, Zoia;Lu, Angela;Porozov, Yuri;Vasylyeva, Tetyana, I;Wertheim, Joel O.;Tierney, Braden T.;Chiu, Charles Y.;Sun, Ren;Wu, Aiping;Abedalthagafi, Malak S.;Pak, Victoria M.;Nagaraj, Shivashankar H.;Smith, Adam L.;Skums, Pavel;Pasaniuc, Bogdan;Komissarov, Andrey;Mason, Christopher E.;Bortz, Eric;Lemey, Philippe;Kondrashov, Fyodor;Beerenwinkel, Niko;Lam, Tommy Tsan-Yuk;Wu, Nicholas C.;Zelikovsky, Alex;Knight, Rob;Crandall, Keith A.;Mangul, Serghei
在 COVID-19 大流行期间，基因组学和生物信息学已成为重要的公共卫生工具。使用这些方法获取的基因组数据支持了全球健康应对措施，促进了测试方法的开发，并允许及时跟踪新的 SARS-CoV-2 变体。然而，快速生成和分析基因组数据几乎无限的潜力也伴随着独特的技术、科学和组织挑战。在这里，我们讨论基因组和计算方法在数据驱动的 COVID-19 响应中的应用、世界各地病毒测序民主化的优势以及与病毒基因组数据收集和处理相关的挑战。
During the COVID-19 pandemic, genomics and bioinformatics have emerged as essential public health tools. The genomic data acquired using these methods have supported the global health response, facilitated development of testing methods, and allowed timely tracking of novel SARS-CoV-2 variants. Yet the virtually unlimited potential for rapid generation and analysis of genomic data is also coupled with unique technical, scientific, and organizational challenges. Here, we discuss the application of genomic and computational methods for the efficient data driven COVID-19 response, advantages of democratization of viral sequencing around the world, and challenges associated with viral genome data collection and processing.
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影响因子：
64.5
作者：
Fauver, Joseph R.;Petrone, Mary E.;Grubaugh, Nathan D.
通讯作者：
Grubaugh, Nathan D.
影响因子：
64.5
作者：
Danko D;Bezdan D;Afshin EE;Ahsanuddin S;Bhattacharya C;Butler DJ;Chng KR;Donnellan D;Hecht J;Jackson K;Kuchin K;Karasikov M;Lyons A;Mak L;Meleshko D;Mustafa H;Mutai B;Neches RY;Ng A;Nikolayeva O;Nikolayeva T;Png E;Ryon KA;Sanchez JL;Shaaban H;Sierra MA;Thomas D;Young B;Abudayyeh OO;Alicea J;Bhattacharyya M;Blekhman R;Castro-Nallar E;Cañas AM;Chatziefthimiou AD;Crawford RW;De Filippis F;Deng Y;Desnues C;Dias-Neto E;Dybwad M;Elhaik E;Ercolini D;Frolova A;Gankin D;Gootenberg JS;Graf AB;Green DC;Hajirasouliha I;Hastings JJA;Hernandez M;Iraola G;Jang S;Kahles A;Kelly FJ;Knights K;Kyrpides NC;Łabaj PP;Lee PKH;Leung MHY;Ljungdahl PO;Mason-Buck G;McGrath K;Meydan C;Mongodin EF;Moraes MO;Nagarajan N;Nieto-Caballero M;Noushmehr H;Oliveira M;Ossowski S;Osuolale OO;Özcan O;Paez-Espino D;Rascovan N;Richard H;Rätsch G;Schriml LM;Semmler T;Sezerman OU;Shi L;Shi T;Siam R;Song LH;Suzuki H;Court DS;Tighe SW;Tong X;Udekwu KI;Ugalde JA;Valentine B;Vassilev DI;Vayndorf EM;Velavan TP;Wu J;Zambrano MM;Zhu J;Zhu S;Mason CE;International MetaSUB Consortium
通讯作者：
International MetaSUB Consortium
DOI：
10.1038/s41576-018-0055-5
发表时间：
2018-12
期刊：
Nature reviews. Genetics
影响因子：
--
作者：
Geoghegan JL;Holmes EC
通讯作者：
Holmes EC
影响因子：
5
作者：
Fahrenfeld, Nicole;Bisceglia, Kevin J.
通讯作者：
Bisceglia, Kevin J.
DOI：
10.1126/science.abf2946
发表时间：
2021-02-12
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
du Plessis L;McCrone JT;Zarebski AE;Hill V;Ruis C;Gutierrez B;Raghwani J;Ashworth J;Colquhoun R;Connor TR;Faria NR;Jackson B;Loman NJ;O'Toole Á;Nicholls SM;Parag KV;Scher E;Vasylyeva TI;Volz EM;Watts A;Bogoch II;Khan K;COVID-19 Genomics UK (COG-UK) Consortium;Aanensen DM;Kraemer MUG;Rambaut A;Pybus OG
通讯作者：
Pybus OG