Diet and exercise in the management of obstructive sleep apnoea and cardiovascular disease risk.
Diet and exercise in the management of obstructive sleep apnoea and cardiovascular disease risk.
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DOI：
10.1183/16000617.0110-2016
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发表时间：
2017-06-30
期刊：
影响因子：
--
通讯作者：
Salas-Salvadó J
中科院分区：
文献类型：
--
作者：
Dobrosielski DA;Papandreou C;Patil SP;Salas-Salvadó J
阻塞性睡眠呼吸暂停（OSA）与心血管疾病（CVD）发病率和死亡率增加有关。公认的是OSA和肥胖通常共存。美国睡眠医学学会建议饮食诱导的减肥和运动作为OSA的生活方式治疗选择。然而，该建议所基于的大多数临床试验都集中在确定热量限制的有效性，通常是低脂饮食改善OSA严重程度，而较少关注通过何种方式实现体重减轻（例如改变饮食质量）或饮食或运动是否介导体重减轻，改善OSA严重程度和CVD底物之间的关联。目前的证据表明，低碳水化合物或地中海饮食对超重和肥胖个体的益处超出了公认的减肥益处。此外，运动对血管健康具有独立的保护作用，这可能会对抗OSA患者中发生的氧化应激，炎症和交感神经激活的增加。本综述旨在扩大我们对饮食和运动对OSA和相关CVD并发症的影响的理解，并为继续研究探索减少OSA患者CVD负担的最佳生活方式策略奠定基础。这篇综述旨在扩大我们对睡眠呼吸暂停患者生活方式干预效果的理解。http://ow.ly/HvlK30bsngt
Obstructive sleep apnoea (OSA) is associated with increased cardiovascular disease (CVD) morbidity and mortality. It is accepted that OSA and obesity commonly coexist. The American Academy of Sleep Medicine recommends dietary-induced weight loss and exercise as lifestyle treatment options for OSA. However, most clinical trials upon which this recommendation is based have focused on establishing the effectiveness of calorie-restricted, often low-fat diets for improving OSA severity, whereas less attention has been given to the means through which weight loss is achieved (e.g. altered dietary quality) or whether diet or exercise mediates the associations between reduced weight, improved OSA severity and the CVD substrate. The current evidence suggests that the benefits of a low-carbohydrate or Mediterranean diet in overweight and obese individuals go beyond the recognised benefits of weight reduction. In addition, exercise has an independent protective effect on vascular health, which may counter the increased oxidative stress, inflammation and sympathetic activation that occur in OSA patients. This review aims to expand our understanding of the effects of diet and exercise on OSA and associated CVD complications, and sets the stage for continued research designed to explore optimal lifestyle strategies for reducing the CVD burden in OSA patients. This review aims to expand our understanding of the effects of lifestyle interventions in sleep apnoea patients http://ow.ly/HvlK30bsngt
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影响因子：
16.2
作者：
Foster GD;Sanders MH;Millman R;Zammit G;Borradaile KE;Newman AB;Wadden TA;Kelley D;Wing RR;Sunyer FX;Darcey V;Kuna ST;Sleep AHEAD Research Group
通讯作者：
Sleep AHEAD Research Group
影响因子：
4.3
作者：
Batool-Anwar, Salma;Goodwin, James L.;Quan, Stuart F.
通讯作者：
Quan, Stuart F.
DOI：
10.1152/ajpendo.1999.276.3.e443
发表时间：
1999-03-01
影响因子：
5.1
作者：
Breslow, MJ;Min-Lee, K;Berkowitz, DE
通讯作者：
Berkowitz, DE
影响因子：
5.8
作者：
Giannopoulou, I;Ploutz-Synder, LL;Kanaley, JA
通讯作者：
Kanaley, JA
影响因子：
120.7
作者：
Gardner, Christopher D.;Kiazand, Alexandre;King, Abby C.
通讯作者：
King, Abby C.