Maintenance, reserve and compensation: the cognitive neuroscience of healthy ageing.

Maintenance, reserve and compensation: the cognitive neuroscience of healthy ageing.
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维持,预订和补偿:健康衰老的认知神经科学。

DOI:
10.1038/s41583-018-0068-2
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发表时间:
2018-11
期刊:
Nature reviews. Neuroscience
影响因子:
--
通讯作者:
Rajah MN
Rajah MN
中科院分区:
其他
文献类型:
--
作者:
Cabeza R;Albert M;Belleville S;Craik FIM;Duarte A;Grady CL;Lindenberger U;Nyberg L;Park DC;Reuter-Lorenz PA;Rugg MD;Steffener J;Rajah MN

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人类认知老化的神经影像学研究为我们理解与年龄相关的认知衰退和成功老化的神经机制带来了重大进展。然而,解释与年龄相关的变化和大脑结构,激活和功能连接的差异是一个持续的挑战。模棱两可的术语是这一挑战的主要来源。例如,术语“补偿”,“维护”和“储备”以不同的方式使用,研究人员不同意解释与这些概念相关的发现所需的证据或结果模式。由于这种不一致性可能会阻碍理论和经验的进步,我们在这里的目的是澄清这些关键术语,并提出共识的定义,维护,储备和补偿。
Human neuroimaging research on cognitive aging has brought significant advances to our understanding of the neural mechanisms underlying age-related cognitive decline and successful aging. However, interpreting age-related changes and differences in brain structure, activation, and functional connectivity is an ongoing challenge. Ambiguous terminology is a major source of this challenge. For example, the terms ‘compensation,’ ‘maintenance,’ and ‘reserve’ are used in different ways and researchers disagree about the kinds of evidence or patterns of results required to interpret findings related to these concepts. As such inconsistencies can impede theoretical and empirical progress, we here aim to clarify these key terms and to propose consensual definitions of maintenance, reserve, and compensation.
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