Mediterranean, DASH, and Alternate Healthy Eating Index Dietary Patterns and Risk of Death in the Physicians' Health Study.
Mediterranean, DASH, and Alternate Healthy Eating Index Dietary Patterns and Risk of Death in the Physicians' Health Study.
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DOI：
10.3390/nu13061893
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发表时间：
2021-05-31
期刊：
影响因子：
5.9
通讯作者：
Djoussé L
中科院分区：
文献类型：
--
作者：
Patel YR;Robbins JM;Gaziano JM;Djoussé L
目的：我们的主要目的是研究地中海饮食（MED）、预防高血压的饮食方法（DASH）和替代健康饮食指数（AHEI）饮食与总死亡率的关系。我们的次要目的是检查这三种饮食模式与心血管疾病（CVD）和癌症死亡率的关系。研究：设计与方法：我们对来自医师健康研究的15,768名男性进行了前瞻性研究，他们完成了半定量的食物频率问卷调查。每种饮食模式的得分被分成五分之一。采用多变量Cox回归模型估计死亡率的风险比（95%置信区间）。结果：基线时平均年龄为65.9±8.9岁。1763人死亡，其中心血管疾病死亡488人，癌症死亡589人。所有饮食评分与全因死亡率风险呈负相关：MED饮食从最低到最高五分位数的全因死亡率风险比（95% CI）分别为1.0（参考）、0.85（0.73-0.98）、0.80（0.69-0.93）、0.77（0.66-0.90）和0.68 (0.58-0.79)；在调整了年龄、能量、吸烟、运动、BMI、高血压、冠心病、充血性心力衰竭、糖尿病、房颤等因素后，DASH饮食的对应值分别为1.0（参考）、0.96（0.82 - 1.12）、0.95（0.82 - 0.95）、0.88（0.77-1.02）、0.69（0.59、0.81）、0.56（0.47-0.67）。对于原因特异性死亡率，MED和AHEI评分与心血管疾病死亡率风险降低呈负相关，而AHEI和MED评分与癌症死亡率风险降低呈负相关。结论：在这组男性医生中，AHEI、MED和DASH评分均与全因死亡率呈负相关。
Objective: Our primary objective was to examine the associations of the Mediterranean (MED), the Dietary Approaches to Stop Hypertension (DASH), and the Alternate Healthy Eating Index (AHEI) diet with total mortality. Our secondary objective was to examine the association of these three dietary patterns with cardiovascular disease (CVD) and cancer mortality. Research: Design and Methods: We prospectively studied 15,768 men from the Physicians’ Health Study who completed a semi-quantitative food-frequency questionnaire. Scores from each dietary pattern were divided into quintiles. Multivariable Cox regression models were used to estimate hazard ratio’s (95% confidence intervals) of mortality. Results: At baseline, average age was 65.9 ± 8.9 years. There were 1763 deaths, including 488 CVD deaths and 589 cancer deaths. All diet scores were inversely associated with risk for all-cause mortality: Hazard ratios (95% CI) of all-cause mortality from lowest to highest quintile for MED diet were 1.0 (reference), 0.85 (0.73–0.98), 0.80 (0.69–0.93), 0.77 (0.66–0.90), and 0.68 (0.58–0.79); corresponding values were 1.0 (reference), 0.96 (0.82–1.12), 0.95 (0.82–1.11), 0.88 (0.75–1.04), and 0.83 (0.71–0.99) for DASH diet and 1.0 (reference), 0.88 (0.77–1.02), 0.82 (0.71–0.95), 0.69 (0.59, 0.81), and 0.56 (0.47–0.67) for AHEI diet, after adjusting for age, energy, smoking, exercise, BMI, hypertension, coronary heart disease, congestive heart failure, diabetes, and atrial fibrillation. For cause-specific mortality, MED and AHEI scores were inversely associated with lower risk for CVD mortality, whereas AHEI and MED scores were inversely associated with lower risk for cancer mortality. Conclusion: Within this cohort of male physicians, AHEI, MED, and DASH scores were each inversely associated with mortality from all causes.
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影响因子：
158.5
作者：
Albert, CM;Campos, H;Ma, J
通讯作者：
Ma, J
影响因子：
7.1
作者：
Bertoia, Monica L.;Triche, Elizabeth W.;Eaton, Charles B.
通讯作者：
Eaton, Charles B.
DOI：
10.1136/bmj.d671
发表时间：
2011-02-22
期刊：
BMJ (Clinical research ed.)
影响因子：
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作者：
Ronksley PE;Brien SE;Turner BJ;Mukamal KJ;Ghali WA
通讯作者：
Ghali WA
影响因子：
7.1
作者：
Harmon, Brook E.;Boushey, Carol J.;Kolonel, Laurence N.
通讯作者：
Kolonel, Laurence N.
影响因子：
37.8
作者：
Mozaffarian D;Appel LJ;Van Horn L
通讯作者：
Van Horn L