Genetic and environmental influences on depressive symptoms in Chinese adolescents.
Genetic and environmental influences on depressive symptoms in Chinese adolescents.
复制标题
遗传和环境对中国青少年抑郁症状的影响
DOI：
10.1007/s10519-013-9632-8
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发表时间：
2014-01
影响因子：
2.6
通讯作者：
Harold, Gordon T.
中科院分区：
文献类型：
--
作者：
Chen, Jie;Li, Xinying;Natsuaki, Misaki N.;Leve, Leslie D.;Harold, Gordon T.
青少年抑郁症在我国十分常见，已成为一个重要的公共卫生问题，但对青少年抑郁症的病因学研究却很少。在本研究中，遗传和环境对中国青少年抑郁症状的影响进行了调查，在1,181双胞胎对居住在北京，中国（11-19岁）。儿童版和父母版的儿童抑郁量表被用来衡量青少年的抑郁症状。对于自我报告，遗传因素，共享环境因素和非共享环境因素分别占抑郁症状变异的50%，5%和45%;对于父母报告，遗传因素，共享环境因素和非共享环境因素分别占变异的51%，18%和31%。这些估计与以前在西方青少年中的研究结果基本一致，支持青少年抑郁症病因模型的跨文化普遍性。无论是定性还是定量的性别差异中发现的病因模型。未来的研究需要探讨基因和环境如何共同作用（基因-环境交互作用，基因-环境相关），以影响中国青少年抑郁症。
Adolescent depression is common and has become a major public health concern in China, yet little research has examined the etiology of depression in Chinese adolescents. In the present study, genetic and environmental influences on Chinese adolescent depressive symptoms were investigated in 1,181 twin pairs residing in Beijing, China (ages 11–19 years). Child- and parent-versions of the children’s depression inventory were used to measure adolescents’ depressive symptoms. For self-reports, genetic factors, shared environmental factors, and non-shared environmental factors accounted for 50, 5, and 45 % of the variation in depressive symptoms, respectively; for parent-reports, genetic factors, shared environmental factors, and non-shared environmental factors accounted for 51, 18, and 31 % of the variation, respectively. These estimates are generally consistent with previous findings in Western adolescents, supporting the cross-cultural generalizability of etiological model of adolescent depression. Neither qualitative nor quantitative sex differences were found in the etiological model. Future studies are needed to investigate how genes and environments work together (gene–environment interaction, gene–environment correlation) to influence depression in Chinese adolescents.
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影响因子：
4.6
作者：
Cole, DA;Tram, JM;Maschman, TL
通讯作者：
Maschman, TL
DOI：
10.1111/j.1469-7610.1997.tb01604.x
发表时间：
1997-10-01
期刊：
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY AND ALLIED DISCIPLINES
影响因子：
--
作者：
Eley, TC
通讯作者：
Eley, TC
DOI：
10.1080/15374416.2010.517159
发表时间：
2010-01-01
影响因子：
4.2
作者：
Hong, Wei;Abela, John R. Z.;Starrs, Claire
通讯作者：
Starrs, Claire
DOI：
10.1111/1469-7610.00038
发表时间：
2002-05-01
期刊：
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY AND ALLIED DISCIPLINES
影响因子：
--
作者：
Happonen, M;Pulkkinen, L;Rose, RJ
通讯作者：
Rose, RJ
影响因子：
3.1
作者：
Byers, Amy L.;Levy, Becca R.;Kasl, Stanislav V.;Bruce, Martha L.;Allore, Heather G.
通讯作者：
Allore, Heather G.