Can a gastric cancer risk survey identify high-risk patients for endoscopic screening? A pilot study.
Can a gastric cancer risk survey identify high-risk patients for endoscopic screening? A pilot study.
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DOI：
10.1016/j.jss.2018.02.053
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发表时间：
2018-07
期刊：
影响因子：
--
通讯作者：
Rapkin BD
中科院分区：
文献类型：
--
作者：
In H;Langdon-Embry M;Gordon L;Schechter CB;Wylie-Rosett J;Castle PE;Margaret Kemeny M;Rapkin BD
一份区分胃癌患病率的变异性与种族/出生国/移民/文化饮食沿着已知风险因素的问卷可能会改善美国胃癌筛查的目标人群。使用现有文献确定项目库。采用聚类分析、焦点小组和认知访谈等方法减少共线项目，完善问卷。Logistic回归分析用于确定哪些项目将胃癌病例与初级保健和社区对照区分开来。对40例病例和100名对照（初级保健=47;社区=53）的数据进行分析，将227个项目库减少到12个项目。使用模型自举对这些变量进行排名后，选择使用排名最高的8个变量的逻辑回归模型作为最终模型。与对照组相比，年龄较大，外国出生，15至18岁时每天食用文化食品，高中教育程度较低以及更大的文化适应与胃癌病例显著相关。一项针对胃癌风险因素、种族、文化习惯和移民模式的8项调查有可能识别出来自美国多文化地区的高风险人群，这些人群可能受益于胃癌内镜筛查。
A questionnaire that distinguishes how variability in gastric cancer prevalence is associated with ethnicity/birth country/immigration/cultural diet along with known risk factors may improve targeting populations for gastric cancer screening in the United States. Existing literature was used to identify the item pool. Cluster analysis, focus groups and cognitive interviewing were used to reduce collinear items and refine the questionnaire. Logistic regression analysis was used to determine which items distinguished gastric cancer cases from the primary care and community controls. Analysis of data from 40 cases and 100 controls (primary care=47; community =53) were used to reduce the 227 item pool to 12 items. After ranking these variables using model bootstrapping, a logistic regression model using the highest ranked 8 variables was chosen as the final model. Older age, foreign nativity, daily consumption of cultural food at ages 15 to 18, less than high-school education and greater acculturation were significantly associated with being a gastric cancer case compared to the controls. An 8-item survey that addresses gastric cancer risk factors, ethnicity, cultural habits and immigration patterns has potential to identify high-risk persons from multicultural areas within the US, who might benefit from endoscopic screening for gastric cancer.
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影响因子：
2.3
作者：
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通讯作者：
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影响因子：
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作者：
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影响因子：
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