Update on SARS research and other possibly zoonotic coronaviruses.

Update on SARS research and other possibly zoonotic coronaviruses.
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DOI:
10.1016/j.ijantimicag.2010.06.016
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发表时间:
2010-11
影响因子:
10.8
通讯作者:
Tong S
Tong S
中科院分区:
医学2区
文献类型:
--
作者:
Anderson LJ;Tong S

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2003年严重急性呼吸系统综合症(萨斯)在全球爆发,导致全球作出了有力和有效的反应,到2003年7月制止了这一疾病的蔓延。此外,当局亦进行了深入而卓有成效的研究工作,以确定病原体、了解该病的临床和流行病学特征、了解该病的发病机制和病毒的分子生物学,以及设计抗病毒药物和疫苗,以治疗和预防该病。在研究SARS的同时,我们检测和鉴定其他新型病毒的能力也在不断提高。SARS的爆发说明了这种检测工具在应对公共卫生威胁方面的重要性。自SARS爆发以来的研究表明,许多新型病毒存在于动物体内,其中一些(但可能不是很多)将对人类构成风险。
The global outbreak of severe acute respiratory syndrome (SARS) in 2003 led to an intense and effective global response that stopped the spread of the disease by July 2003. There was also an intensive and very productive research effort to identify the aetiological agent, characterise the clinical and epidemiological features of the disease, understand the pathogenesis of the disease and the molecular biology of the virus, and design antiviral drugs and vaccines to treat and prevent the disease. In parallel with the SARS research effort there have been continuous improvements in our ability to detect and characterise other novel viruses. The SARS outbreak illustrates the importance of such detection tools in the response to public health threats. Studies since the SARS outbreak suggest that many novel viruses exist in animals and some, but probably not many, will present a risk to humans.
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