Antibacterial Effects of Modified Implant Abutment Surfaces for the Prevention of Peri-Implantitis-A Systematic Review.

Antibacterial Effects of Modified Implant Abutment Surfaces for the Prevention of Peri-Implantitis-A Systematic Review.
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DOI:
10.3390/antibiotics10111350
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发表时间:
2021-11-05
期刊:
Antibiotics (Basel, Switzerland)
影响因子:
--
通讯作者:
Schmidt F
Schmidt F
中科院分区:
其他
文献类型:
--
作者:
Jennes ME;Naumann M;Peroz S;Beuer F;Schmidt F

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本研究的目的是系统地回顾有关抗菌种植体基台表面或涂层的研究,这些研究可能抑制细菌生长以预防菌斑引起的种植体周围炎症性疾病。在确定病例、测定/实验室程序、谓词/参考标准和结果(CAPO)后收集数据。通过数据库检索,确定了720条记录。经过筛选,9篇出版物符合纳入标准并被纳入。以下表面/涂层表现出抗菌性能:用阳极火花沉积技术对钛进行电化学表面改性;多西环素阴极极化涂层;直流等离子溅射镀银;氮化钛;氮化锆及微波辅助纳米银涂层。由于文献的现状是描述性的,所以没有进行meta分析。虽然一些基牙涂层显示出抗菌能力,但其中一些也会影响所研究的人类细胞的行为。没有一项研究调查了表面修饰的长期影响。由于表面变化是抗菌作用发展的主要因素,因此必须对生物降解行为进行表征以了解其持久性。迄今为止,还没有有效的结构、材料或策略来避免种植体周围的炎症作为临床常规。此外,临床研究很少。
The aim of the present study was to systematically review studies investigating antibacterial implant abutment surfaces or coatings, which may suppress bacterial growth to prevent plaque-induced peri-implant inflammatory disease. Data were collected after identification of case, assay/laboratory procedure, predicate/reference standard and outcome (CAPO). Seven hundred and twenty (720) records were identified through data base searching. After screening nine publications fulfilled inclusion criteria and were included. The following surfaces/coatings showed antibacterial properties: Electrochemical surface modification of titanium by the anodic spark deposition technique; doxycycline coating by cathodic polarization; silver coating by DC plasma sputter; titanium nitride; zirconium nitride and microwave assistant nano silver coating. Since the current state of the literature is rather descriptive, a meta-analysis was not performed. While several abutment coatings showed to have antibacterial capacity, some of them also influenced the behavior of investigated human cells. None of the studies investigated the long-term effect of surface modifications. Since surface changes are the main contributing factor in the development of antibacterial effects, the biodegradation behavior must be characterized to understand its durability. To date there is no effective structure, material or strategy to avoid peri-implant inflammation used as clinical routine. Furthermore, clinical studies are scarce.
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