Occupational exposures and cancer risk in commercial laundry and dry cleaning industries: a scoping review.
Occupational exposures and cancer risk in commercial laundry and dry cleaning industries: a scoping review.
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DOI：
10.1186/s12889-023-17306-y
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发表时间：
2023-12-21
影响因子：
4.5
通讯作者：
中科院分区：
文献类型：
--
作者：
洗衣和干洗行业对于维持我们日常生活的清洁和卫生至关重要。然而，它们也被认定为工人接触有害化学物质的源头，可能会对健康产生严重影响。尽管越来越多的证据表明四氯乙烯和三氯乙烯等溶剂具有致癌性，但它们在该行业中仍然普遍使用。此外，虽然鉴于对健康和环境不良影响的迹象，替代溶剂的使用日益增加，但我们对接触这些新试剂的潜在风险的了解仍存在重大差距。
本研究旨在确定有关洗衣和干洗行业工人接触当代有毒化学物质及其相关致癌风险的文献中的空白。为实现这一目标，对2012年至2022年的同行评审出版物进行了范围综述，重点关注详细描述洗衣和干洗行业内化学物质接触、采样方法和工人情况的研究。
在这次范围综述中，对12篇相关论文进行了评估。大多数（66%）研究了四氯乙烯的接触情况，一个值得注意的发现是，即使干洗工接触的四氯乙烯水平低于职业接触限值，他们的生物标志物也有显著的微核频率和DNA损伤。同样，另一项研究也支持了这些结果，发现接触工人的早期DNA损伤有所增加。对三氯乙烯和苯的单独研究呈现出不同的接触水平和健康风险，由于它们被国际癌症研究机构归为1类致癌物，这引起了人们的关注。关于替代溶剂的信息有限，凸显了健康结果数据、接触指南和致癌分类方面的差距。
关于健康结果的研究，特别是干洗中溶剂接触的致癌性研究有限，66%的研究没有监测健康影响，尤其是对于新兴溶剂。此外，研究结果表明四氯乙烯即使低于规定的职业限值也可能造成DNA损伤，这强调了重新评估安全限值的必要性。随着丁基醇和高闪点碳氢化合物等替代溶剂变得更加普遍，有必要对接触它们的影响进行调查，以保障工人的健康。本次范围综述已在开放科学框架注册，注册DOI：10.17605/OSF.IO/Q8FR3。
网络版包含补充材料，可在10.1186/s12889 - 023 - 17306 - y获取。
The laundry and dry cleaning industries are critical for maintaining cleanliness and hygiene in our daily lives. However, they have also been identified as sources of hazardous chemical exposure for workers, leading to potentially severe health implications. Despite mounting evidence that solvents like perchloroethylene and trichloroethylene are carcinogenic, they remain commonly used in the industry. Additionally, while alternative solvents are increasingly being utilized in response to indications of adverse health and environmental effects, there remains a significant gap in our understanding of the potential risks associated with exposure to these new agents. This study aims to identify gaps in the literature concerning worker exposure to contemporary toxic chemicals in the laundry and dry cleaning industry and their associated carcinogenic risks. A scoping review of peer-reviewed publications from 2012 to 2022 was conducted to achieve this objective, focusing on studies that detailed chemical exposures, sampling methods, and workers within the laundry and dry cleaning sector. In this scoping review, 12 relevant papers were assessed. A majority (66%) examined perchloroethylene exposure, with one notable finding revealing that biomarkers from dry cleaners had significant micronuclei frequency and DNA damage, even when exposed to PCE at levels below occupational exposure limits. Similarly, another study supported these results, finding an increase in early DNA damage among exposed workers. Separate studies on TCE and benzene presented varied exposure levels and health risks, raising concern due to their IARC Group 1 carcinogen classification. Information on alternative solvents was limited, highlighting gaps in health outcome data, exposure guidelines, and carcinogenic classifications. Research on health outcomes, specifically carcinogenicity from solvent exposure in dry cleaning, is limited, with 66% of studies not monitoring health implications, particularly for emerging solvents. Further, findings indicated potential DNA damage from perchloroethylene, even below set occupational limits, emphasizing the need to reevaluate safety limits. As alternative solvents like butylal and high-flashpoint hydrocarbons become more prevalent, investigations into the effects of their exposure are necessary to safeguard workers’ health. This scoping review is registered with the Open Science Framework, registration DOI: 10.17605/OSF.IO/Q8FR3. The online version contains supplementary material available at 10.1186/s12889-023-17306-y.
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影响因子：
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Bonassi S;Norppa H;Ceppi M;Strömberg U;Vermeulen R;Znaor A;Cebulska-Wasilewska A;Fabianova E;Fucic A;Gundy S;Hansteen IL;Knudsen LE;Lazutka J;Rossner P;Sram RJ;Boffetta P
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影响因子：
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Arnold SM;Angerer J;Boogaard PJ;Hughes MF;O'Lone RB;Robison SH;Schnatter AR
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影响因子：
3.3
作者：
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通讯作者：
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影响因子：
10.4
作者：
Scott, Cheryl Siegel;Chiu, Weihsueh A
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