Patient characteristics associated with artifacts in Spectralis optical coherence tomography imaging of the retinal nerve fiber layer in glaucoma.

Patient characteristics associated with artifacts in Spectralis optical coherence tomography imaging of the retinal nerve fiber layer in glaucoma.
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DOI:
10.1016/j.ajo.2014.12.006
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发表时间:
2015-03
影响因子:
4.2
通讯作者:
Chen, Teresa C.
Chen, Teresa C.
中科院分区:
医学1区
文献类型:
--
作者:
Liu, Yingna;Simavli, Huseyin;Que, Christian John;Rizzo, Jennifer L.;Tsikata, Edem;Maurer, Rie;Chen, Teresa C.

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确定与Spectralis光学相干断层扫描(OCT)视网膜神经纤维层(RNFL)扫描中伪影相关的患者因素和眼部状况。回顾性横断面研究。在对2009年9月至2013年7月期间使用Spectralis OCT扫描进行完整眼科检查的1188名患者的2313次眼部扫描的审查中,描述了12种伪影类型的患病率。利用广义估计方程模型分析伪影患病率增加与10个患者特征之间的相关性,这些特征包括年龄、性别、种族、视力、屈光不正、散光、白内障状态、青光眼分期、视野可靠性和青光眼诊断。总共有1070或46.3%的2313眼扫描至少有一个伪影。偏心误差是最常见的伪影(27.8%),其次是玻璃体后脱离伪影(14.4%)。视力低于20/40(p<0.0001)、存在中度至重度白内障(p<0.0001)、青光眼晚期(p<0.0001)和开角型青光眼(p=0.0003)与伪影患病率增加相关。临床医生在根据RNFL厚度测量做出治疗决定之前,应首先评估扫描伪影。
To determine patient factors and eye conditions associated with artifacts in Spectralis optical coherence tomography (OCT) retinal nerve fiber layer (RNFL) scans. Retrospective cross-sectional study. The prevalence of twelve artifact types were described in this review of 2313 eye scans from 1188 patients who underwent a complete eye exam with Spectralis OCT scanning during the period of September 2009 to July 2013. Generalized estimating equations model was utilized to analyze associations between increased artifact prevalence and 10 patient characteristics, which included age, sex, race, visual acuity, refractive error, astigmatism, cataract status, glaucoma staging, visual field reliability, and glaucoma diagnosis. A total of 1070 or 46.3% of the 2313 eye scans had at least one artifact. De-centration error was the most common artifact (27.8%), followed by posterior vitreous detachment artifacts (14.4%). Visual acuity of less than 20/40 (p<0.0001), presence of moderate to severe cataracts (p<0.0001), advanced stage of glaucoma (p<0.0001), and a diagnosis of open angle glaucoma (p=0.0003) were associated with increased prevalence of artifacts. Clinicians should first assess scans for artifacts before making therapeutic decisions based on RNFL thickness measurements.
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