Scaling the primate lateral geniculate nucleus: niche and neurodevelopment in the regulation of magnocellular and parvocellular cell number and nucleus volume.
Scaling the primate lateral geniculate nucleus: niche and neurodevelopment in the regulation of magnocellular and parvocellular cell number and nucleus volume.
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DOI：
10.1002/cne.23505
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发表时间：
2014-06-01
期刊：
影响因子：
--
通讯作者：
de Lima Silveira LC
中科院分区：
文献类型：
--
作者：
Finlay BL;Charvet CJ;Bastille I;Cheung DT;Muniz JA;de Lima Silveira LC
新的体视学评估的外侧膝状体核（LGN）神经元的数量和体积在五个新的世界灵长类动物（Cebus apella，Saguinus midas尼日尔，Alouatta caraya，Aotus azarae，Callicebus moloch）和编译LGN卷的另外26种哺乳动物进行了分析，以更好地了解视觉系统的进化。在灵长类动物中，大细胞（M）和小细胞（P）细胞群均随脑体积异速生长，P细胞具有显著更高的斜率，使得M神经元数量每增加一次，P神经元数量就增加一倍以上（ln标度; y = 0.89x + 2.42，R2 = 0.664）。在白天活动的灵长类动物中，P细胞与M细胞的比例略高于夜间活动的灵长类动物，但差异显著。对于所有的哺乳动物，包括灵长类动物，LGN体积是无关的夜间或昼夜生态位，但表现出显着的差异，根据分类组的斜率和截距。M和P细胞的异速生长比例可以与神经发生的顺序相关，与早期产生的M细胞相比，晚期产生的P细胞以正异速生长增加。这种发育规律性将相对中央凹代表性与相对同皮质扩大联系起来，这也是后期产生的。在白天活动的灵长类动物中，P/M细胞比率的小幅增加可能是由于M细胞群体中发育神经元损失的增加，因为它竞争初级视觉皮层中有限的终止区。
New stereological assessments of lateral geniculate nucleus (LGN) neuron numbers and volumes in five New World primates (Cebus apella, Saguinus midas niger, Alouatta caraya, Aotus azarae, and Callicebus moloch) and compiled LGN volumes for an additional 26 mammals were analyzed for a better understanding of visual system evolution. Both the magnocellular (M)- and the parvocellular (P)-cell populations scale allometrically with brain volume in primates, P cells with a significantly higher slope such that, for every increase in M neuron number, P neuron numbers more than double (ln scale; y = 0.89x + 2.42, R2 = 0.664). In diurnal primates, the ratio of P to M cells was slightly but significantly higher than in nocturnal primates. For all mammals, including primates, LGN volume was unrelated to nocturnal or diurnal niche but showed marked differences in slope and intercept depending on taxonomic group. The allometric scaling of M and P cells can be related to the order of neurogenesis, with late-generated P cells increasing with positive allometry compared with the earlier-generated M cells. This developmental regularity links relative foveal representation to relative isocortex enlargement, which is also generated late. The small increase in the P/M cell ratio in diurnal primates may result from increased developmental neuron loss in the M-cell population as it competes for limited termination zones in primary visual cortex.
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影响因子：
64.8
作者：
AZZOPARDI, P;COWEY, A
通讯作者：
COWEY, A
影响因子：
2.5
作者：
Chalfin, Brandon P.;Cheung, Desmond T.;Finlay, Barbara L.
通讯作者：
Finlay, Barbara L.
灵长类同皮质神经元密度和数量的系统性平衡梯度。
影响因子：
2.9
作者：
Cahalane DJ;Charvet CJ;Finlay BL
通讯作者：
Finlay BL
影响因子：
2.9
作者：
FIELD, DJ
通讯作者：
FIELD, DJ
影响因子：
1.9
作者：
Blasco, B;Avenda単o, C;Cavada, C
通讯作者：
Cavada, C