Sialographic Analysis of Radioiodine-Associated Chronic Sialadenitis.

Sialographic Analysis of Radioiodine-Associated Chronic Sialadenitis.
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DOI:
10.1002/lary.29279
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发表时间:
2021-05
期刊:
影响因子:
2.6
通讯作者:
Hoffman, Henry T.
Hoffman, Henry T.
中科院分区:
医学2区
文献类型:
--
作者:
Thorpe, Ryan K.;Foggia, Megan J.;Marcus, Kathryn S.;Policeni, Bruno;Maley, Joan E.;Hoffman, Henry T.

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应用一种新的涎腺造影分类系统来识别I-131治疗后的腮腺和下颌下导管结果,并评估与剂量和症状持续时间的相关性。通过回顾性病历审查确定了既往接受I-131治疗后在2008年2月至2019年2月期间接受涎腺造影术的患者。通过应用爱荷华州腮腺造影量表对他们的涎腺造影进行系统评价和评分,同时包括颌下腺分析。在337张涎腺造影片中,30张(下颌下5张,腮腺25张)进行了分析。在所有的涎管造影中均发现了导管狭窄,7/30例病例的导管狭窄被分级为中度(>50-75%),15/30例病例的导管狭窄被分级为重度(>75%)。23/30例远端(主)胆管狭窄。未发现导管狭窄程度与I-131剂量(p=0.39)、年龄(p=0.81)或从I-131治疗到涎管造影的时间(p=0.97)之间存在关联。爱荷华州腮腺涎管造影量表成功地应用于报告腮腺和颌下导管系统的异常。碘-131相关性涎腺炎最常见的表现是远端涎腺导管严重狭窄。未发现导管狭窄程度与I-131剂量、年龄或症状持续时间之间存在统计学显著相关性。
To apply a novel sialography classification system to identify parotid and submandibular ductal findings following I-131 therapy and to assess correlates to dose and duration of symptoms. Patients who underwent sialography between February 2008 and February 2019 after previously receiving I-131 treatment were identified via a retrospective chart review. Their sialograms were systematically evaluated and scored by applying the Iowa parotid sialogram scale to also include submandibular gland analysis. From 337 sialograms, 30 (5 submandibular, 25 parotid) underwent analysis. Ductal stenosis was identified in all sialograms and was graded as moderate ( >50-75%) in 7/30 cases and severe ( >75%) in 15/30 cases. The distal (main) duct was narrowed in 23/30 cases. No association was identified between degree of ductal stenosis and I-131 dose (p=0.39), age (p=0.81), or time from I-131 therapy to sialogram (p=0.97). The Iowa parotid sialogram scale was successfully applied to report abnormalities of the parotid and submandibular ductal system. The most common manifestation of I-131-associated sialadenitis was a severe stenosis within the distal salivary duct. No statistically significant association was found between degree of ductal stenosis and dose of I-131, age, or duration of symptoms.
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