Turning males on: activation of male courtship behavior in Drosophila melanogaster.

Turning males on: activation of male courtship behavior in Drosophila melanogaster.
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DOI:
10.1371/journal.pone.0021144
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发表时间:
2011
期刊:
影响因子:
3.7
通讯作者:
Baker BS
Baker BS
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Pan Y;Robinett CC;Baker BS

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果蝇雄性的先天性性行为是一个很有吸引力的系统,可以用来阐明复杂的行为模式是如何产生的。D.男性性行为的可能性黑腹果蝇是由无果(fruitless)和多空(doubletex)性别调节基因所指定的。我们使用温度敏感性激活剂dTRPA1探测男性求偶行为中的fruM和dsx表达神经元的作用。几乎所有的求爱步骤,从求爱歌射精,可以诱导在非常高的水平,通过激活所有的fruM或所有dsx神经元在孤独的男性。详细的描述揭示了不同的角色fruM和dsx在男性求偶。令人惊讶的是,当所有dsx神经元都被激活时,用于配偶辨别的系统仍然工作良好,但是当所有fruM神经元都被激活时,该系统受损。最引人注目的是,我们提供了一个fruM独立的求爱途径,主要是视觉依赖的证据。
The innate sexual behaviors of Drosophila melanogaster males are an attractive system for elucidating how complex behavior patterns are generated. The potential for male sexual behavior in D. melanogaster is specified by the fruitless (fru) and doublesex (dsx) sex regulatory genes. We used the temperature-sensitive activator dTRPA1 to probe the roles of fruM- and dsx-expressing neurons in male courtship behaviors. Almost all steps of courtship, from courtship song to ejaculation, can be induced at very high levels through activation of either all fruM or all dsx neurons in solitary males. Detailed characterizations reveal different roles for fruM and dsx in male courtship. Surprisingly, the system for mate discrimination still works well when all dsx neurons are activated, but is impaired when all fruM neurons are activated. Most strikingly, we provide evidence for a fruM-independent courtship pathway that is primarily vision dependent.
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