Physical activity, fitness, and gray matter volume.
Physical activity, fitness, and gray matter volume.
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DOI：
10.1016/j.neurobiolaging.2014.03.034
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发表时间：
2014-09
影响因子：
4.2
通讯作者：
Weinstein AM
中科院分区：
文献类型：
--
作者：
Erickson KI;Leckie RL;Weinstein AM
在这篇综述中，我们探讨了身体活动，心肺功能和运动对老年人灰质体积之间的关系。我们的结论是，较高的心肺健康水平通常与前额叶皮层和海马体中较大的灰质体积相关，而在其他区域则不太一致。我们还得出结论，体力活动与更大的灰质体积在同一地区，与心肺健康，包括前额叶皮层和海马体。文献中的一些异质性可以用年龄、压力或其他因素的效应调节来解释。最后，我们报告了来自随机运动干预的有希望的结果，这些结果表明海马体和前额叶皮质的体积保持柔韧性，并对中等强度的运动有反应，持续6个月至1年。身体活动似乎是影响成年后期灰质体积的有利方法，但有必要进行额外的良好对照研究，以告知公共政策运动对脑容量的潜在保护或治疗作用。
In this review we explore the association between physical activity, cardiorespiratory fitness, and exercise on gray matter volume in older adults. We conclude that higher cardiorespiratory fitness levels are routinely associated with greater gray matter volume in the prefrontal cortex and hippocampus, and less consistently in other regions. We also conclude that physical activity is associated with greater gray matter volume in the same regions that are associated with cardiorespiratory fitness including the prefrontal cortex and hippocampus. Some heterogeneity in the literature may be explained by effect moderation by age, stress, or other factors. Finally, we report promising results from randomized exercise interventions that suggest that the volume of the hippocampus and prefrontal cortex remain pliable and responsive to moderate intensity exercise for 6-months to 1-year. Physical activity appears to be a propitious method for influencing gray matter volume in late adulthood, but additional well-controlled studies are necessary to inform public policies about the potential protective or therapeutic effects of exercise on brain volume.
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影响因子：
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