Plasticity of defensive behavior and fear in early development.
Plasticity of defensive behavior and fear in early development.
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DOI：
10.1016/j.neubiorev.2008.11.004
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发表时间：
2009-03
影响因子：
8.2
通讯作者：
Wiedenmayer, Christoph P.
中科院分区：
文献类型：
--
作者：
Wiedenmayer, Christoph P.
动物有能力以一系列的防御行为来应对威胁性的情况。这篇综述表明，防御行为的变化在哺乳动物的早期生活。首先，未习得的反应在早期个体发育过程中被重组，并以特定年龄的方式表达。第二，防御反应的表达受到第一次遇到威胁之前的早期经验的影响。第三，一旦动物受到威胁性刺激，它们就会改变自己的行为。防御行为的神经基础和在发展过程中改变它们的过程进行了讨论。恐惧回路的组件和连接的成熟似乎有助于未习得的恐惧反应的变化。早期的经验和学习改变了这些发展过程，并塑造了防御行为的表达。在个体发育过程中，神经基质和防御行为的持续重组似乎使动物能够适应在给定年龄和给定环境中遇到的条件。防御行为的发展变化可以被概念化为表型可塑性。
Animals have the ability to respond to threatening situations with sets of defensive behaviors. This review demonstrates that defensive behaviors change during early life in mammals. First, unlearned responses are reorganized during early ontogeny and expressed in an age-specific way. Second, the expression of defensive responses is influenced by early experience prior to the first encounter with a threat. Third, once animals have been exposed to a threatening stimulus they subsequently modify their behavior. The neural bases of defensive behavior and the processes that alter them during development are discussed. Maturation of components and connections of the fear circuit seem to contribute to changes in unlearned fear responses. Early experience and learning modify these developmental processes and shape the expression of defensive behavior. Continuous reorganization of the neural substrate and defensive behavior during ontogeny seems to allow the animal to adjust to the conditions it encounters at a given age in a given environment. It is proposed that the developmental changes in defensive behavior can be conceptualized as phenotypic plasticity.
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影响因子：
7.6
作者：
Andersen, SL;Teicher, MH
通讯作者：
Teicher, MH
影响因子：
8.2
作者：
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通讯作者：
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DOI：
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发表时间：
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影响因子：
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通讯作者：
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DOI：
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发表时间：
1976-01-01
期刊：
JOURNAL OF COMPARATIVE AND PHYSIOLOGICAL PSYCHOLOGY
影响因子：
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作者：
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通讯作者：
HIRSCH, SM
影响因子：
2.5
作者：
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通讯作者：
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