A cornucopia of human polyomaviruses.
A cornucopia of human polyomaviruses.
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DOI:
10.1038/nrmicro2992
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发表时间:
2013-04
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影响因子:
--
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中科院分区:
文献类型:
--
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During the past 6 years, focused virus hunting has led to the discovery of nine new human polyomaviruses, including Merkel cell polyomavirus, which has been linked to Merkel cell carcinoma, a lethal skin cell cancer. The discovery of so many new and highly divergent human polyomaviruses raises key questions regarding their evolution, tropism, latency, reactivation, immune evasion and contribution to disease. This Review describes the similarities and differences among the new human polyomaviruses and discusses how these viruses might interact with their human host.
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