Analysis of 2-[Fluorine-18]-Fluoro-2-deoxy-D-glucose uptake kinetics in PET studies of pulmonary inflammation.
Analysis of 2-[Fluorine-18]-Fluoro-2-deoxy-D-glucose uptake kinetics in PET studies of pulmonary inflammation.
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DOI:
10.1016/j.acra.2010.11.019
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发表时间:
2011-04
影响因子:
4.8
通讯作者:
Venegas, Jose G.
中科院分区:
文献类型:
--
作者:
Schroeder, Tobias;Melo, Marcos F. Vidal;Venegas, Jose G.
关键词:
Dynamic positron emission tomography (PET) imaging of the lung using the radiotracer 2-[fluorine-18]-fluoro-2-deoxy-D-glucose (18F-FDG) is an emerging method to assess noninvasively the metabolic activity of pulmonary inflammatory cells. Nevertheless, because of the distinct functional and structural characteristics of inflamed lung tissue standard methods of 18F-FDG analysis can be substantially limited and there is no consensus about the best method for quantification of the 18F-FDG signal for acute or chronic inflammatory lung diseases. This article gives an overview on recent advances in quantitative analysis of 18F-FDG uptake kinetics in non-neoplastic inflamed lung tissue.
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DOI:
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