Striatal Dopamine and the Interface between Motivation and Cognition.

Striatal Dopamine and the Interface between Motivation and Cognition.
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纹状体多巴胺以及动机与认知之间的接口。

DOI:
10.3389/fpsyg.2011.00163
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发表时间:
2011
影响因子:
3.8
通讯作者:
Cools R
Cools R
中科院分区:
心理学3区
文献类型:
--
作者:
Aarts E;van Holstein M;Cools R

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人们早就知道,大脑中的多巴胺与食欲动机和认知有关。最近的研究表明,多巴胺也在食欲动机和认知之间的相互作用中发挥作用。在这里,我们回顾这项工作。动物研究揭示了中脑和纹状体之间螺旋式连接的安排,这有助于多巴胺将信息流从腹内侧区引导到纹状体更背部的区域。根据目前关于多巴胺对认知的影响的认识,我们假设这些纹状体-黑质-纹状体联系为食欲动机对认知的特定功能影响提供了基础。这一假设的一个含义是,食欲动机可以根据任务要求而导致认知改善或损害。
Brain dopamine has long been known to be implicated in the domains of appetitive motivation and cognition. Recent work indicates that dopamine also plays a role in the interaction between appetitive motivation and cognition. Here we review this work. Animal work has revealed an arrangement of spiraling connections between the midbrain and the striatum that subserves a mechanism by which dopamine can direct information flow from ventromedial to more dorsal regions in the striatum. In line with current knowledge about dopamine's effects on cognition, we hypothesize that these striato-nigro-striatal connections provide the basis for functionally specific effects of appetitive motivation on cognition. One implication of this hypothesis is that appetitive motivation can induce cognitive improvement or impairment depending on task demands.
DOI: 10.1016/j.biopsych.2011.03.028
发表时间: 2011-06-15
影响因子: 10.6
作者:
Cools, Roshan;D'Esposito, Mark
通讯作者: D'Esposito, Mark
DOI: 10.1037/0735-7044.114.1.3
发表时间: 2000-02-01
影响因子: 1.9
作者:
Collins, P;Wilkinson, LS;Roberts, AC
通讯作者: Roberts, AC
DOI: 10.1016/s0028-3932(03)00117-9
发表时间: 2003-01-01
期刊: NEUROPSYCHOLOGIA
影响因子: 2.6
作者:
Cools, R;Barker, RA;Robbins, TW
通讯作者: Robbins, TW
DOI: 10.1162/jocn.2010.21435
发表时间: 2011-03-01
影响因子: 3.2
作者:
Aarts, Esther;Roelofs, Ardi
通讯作者: Roelofs, Ardi
DOI: 10.1093/cercor/11.12.1136
发表时间: 2001-12-01
期刊: CEREBRAL CORTEX
影响因子: 3.7
作者:
Cools, R;Barker, RA;Robbins, TW
通讯作者: Robbins, TW