Antidiabetic Effects of Aronia melanocarpa and Its Other Therapeutic Properties.
Antidiabetic Effects of Aronia melanocarpa and Its Other Therapeutic Properties.
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DOI：
10.3389/fnut.2017.00053
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发表时间：
2017
影响因子：
5
通讯作者：
Waisundara VY
中科院分区：
文献类型：
--
作者：
Banjari I;Misir A;Šavikin K;Jokić S;Molnar M;De Zoysa HKS;Waisundara VY
糖尿病是一种全球性流行病，由于其患病率和经济负担的增加，需要紧急关注。因此，鉴于目前药物治疗的无效性，正在研究许多替代疗法的抗糖尿病特性。从这个角度来看，黑果腺肋花楸（Aronia melanocarpa或black chokeberry）已在许多研究中研究了其治疗特性，特别是其对抗高血糖诱导的氧化应激和糖尿病大血管并发症（包括心血管疾病）的能力。虽然A.黑果榄原产于北美东部地区，在欧洲和亚洲也有广泛种植。几项体内研究显示了A.在大鼠模型中观察到黑果莓果汁和植物提取物的氧化应激标记物显著降低。一些有效的生物活性化合物存在于水果和植物的其他部分被确定为（−）-表儿茶素，绿原酸，新绿原酸和矢车菊素-3-半乳糖苷。总体而言，A.黑果芸香可以被认为是抗氧化剂的良好来源，其在对抗高血糖诱导的氧化应激中是有效的。
Diabetes is a global pandemic which warrants urgent attention due to its rising prevalence and economic burden. Thus, many alternative therapies are being researched for antidiabetic properties, given the inefficacy of current medicinal treatments. From this perspective, Aronia melanocarpa or black chokeberry has been investigated for its therapeutic properties in many studies, especially for its ability to combat hyperglycemia-induced oxidative stress and the macrovascular complications of diabetes including cardiovascular disease. Though A. melanocarpa is native to the eastern areas of North America, it has been planted extensively in Europe and Asia as well. Several in vivo studies have displayed the antioxidant properties of A. melanocarpa berry juice and plant extract in rat models where oxidative stress markers were observed to have significant reductions. Some of the potent bioactive compounds present in the fruits and other parts of the plant were identified as (−)-epicatechin, chlorogenic acid, neochlorogenic acid, and cyanidin-3-galactoside. Overall, A. melanocarpa could be considered a good source of antioxidants which is effective in combating hyperglycemia-induced oxidative stress.
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DOI：
10.3390/molecules22060944
发表时间：
2017-06-07
期刊：
Molecules (Basel, Switzerland)
影响因子：
--
作者：
Jurikova T;Mlcek J;Skrovankova S;Sumczynski D;Sochor J;Hlavacova I;Snopek L;Orsavova J
通讯作者：
Orsavova J
影响因子：
2.4
作者：
Kardum, Nevena;Milovanovic, Branislav;Spasic, Slavica
通讯作者：
Spasic, Slavica
影响因子：
5.5
作者：
Meraya, Abdulkarim M.;Raval, Amit D.;Sambamoorthi, Usha
通讯作者：
Sambamoorthi, Usha
影响因子：
1.3
作者：
Nowak, Dariusz;Grabczewska, Zofia;Kubica, Jacek
通讯作者：
Kubica, Jacek
影响因子：
5.6
作者：
Kardum, Nevena;Takic, Marija;Konic-Ristic, Aleksandra
通讯作者：
Konic-Ristic, Aleksandra