Milk Consumption and Respiratory Function in Asthma Patients: NHANES Analysis 2007-2012.

Milk Consumption and Respiratory Function in Asthma Patients: NHANES Analysis 2007-2012.
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DOI:
10.3390/nu13041182
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发表时间:
2021-04-02
期刊:
影响因子:
5.9
通讯作者:
Nordgren TM
Nordgren TM
中科院分区:
医学2区
文献类型:
--
作者:
Sveiven SN;Bookman R;Ma J;Lyden E;Hanson C;Nordgren TM

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根据疾病控制和预防中心的数据,自20世纪80年代以来,哮喘患病率稳步上升。利用国家健康与营养调查(NHANES)的数据,我们调查了牛奶消费量与肺功能(PF)之间的关系。在合格的总成人人群中进行多变量分析,调整肺功能的先验潜在混杂因素(n = 11,131)和那些自我报告哮喘(n = 1,542),包括以下变量:牛奶消耗量、哮喘诊断、用力肺活量(FVC)、FVC%预测值(%)、一秒用力呼气量(FEV 1)、FEV1%和FEV 1/FVC。在总人群中,FEV1%和FVC%与前30天内仅常规(每周5天以上)摄入1%牛奶显著相关(β:1.81; 95% CI:[0.297,3.325]; p = 0.020和β:1.27; [0.16,3.22]; p = 0.046)。在哮喘受试者中,一生中不同规律的牛奶摄入量与FVC(β:127.3; 95% CI:[13.1,241.4]; p = 0.002)和FVC%(β:2.62; 95% CI:[0.44,4.80]; p = 0.006)显著相关。牛奶摄入量与FEV 1/FVC之间无相关性,而牛奶类型有不同的影响和意义。总之,我们发现在正常人群和哮喘人群中,某些牛奶消费倾向与肺功能值相关。这些发现提出了未来对乳制品消费在改变肺功能和哮喘结局方面的潜在作用的研究,对保护和维持肺部健康具有潜在影响。
Per the Centers for Disease Control and Prevention, asthma prevalence has steadily risen since the 1980s. Using data from the National Health and Nutrition Examination Survey (NHANES), we investigated associations between milk consumption and pulmonary function (PF). Multivariable analyses were performed, adjusted for a priori potential confounders for lung function, within the eligible total adult population (n = 11,131) and those self-reporting asthma (n = 1,542), included the following variables: milk-consumption, asthma diagnosis, forced vital capacity (FVC), FVC%-predicted (%), forced expiratory volume in one-second (FEV1), FEV1% and FEV1/FVC. Within the total population, FEV1% and FVC% were significantly associated with regular (5+ days weekly) consumption of exclusively 1% milk in the prior 30-days (β:1.81; 95% CI: [0.297, 3.325]; p = 0.020 and β:1.27; [0.16, 3.22]; p = 0.046). Among participants with asthma, varied-regular milk consumption in a lifetime was significantly associated with FVC (β:127.3; 95% CI: [13.1, 241.4]; p = 0.002) and FVC% (β:2.62; 95% CI: [0.44, 4.80]; p = 0.006). No association between milk consumption and FEV1/FVC was found, while milk-type had variable influence and significance. Taken together, we found certain milk consumption tendencies were associated with pulmonary function values among normal and asthmatic populations. These findings propound future investigations into the potential role of dairy consumption in altering lung function and asthma outcomes, with potential impact on the protection and maintenance of pulmonary health.
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