Working memory capacity and addiction treatment outcomes in adolescents.
Working memory capacity and addiction treatment outcomes in adolescents.
复制标题
青少年的工作记忆能力和成瘾治疗结果。
DOI：
10.1080/00952990.2017.1344680
复制
发表时间：
2018
期刊：
影响因子：
--
通讯作者：
Feldstein Ewing SW
中科院分区：
文献类型：
--
作者：
Houck JM;Feldstein Ewing SW
包括动机访谈（MI）在内的短暂成瘾治疗已在青少年中显示出希望，但影响该人群治疗效果的因素仍然未知。其中一个候选者是工作记忆，即记住事实或想法的能力。这是相关的，因为在治疗中，客户在与临床医生合作时必须保持和操纵想法。工作记忆取决于大脑结构和功能，这些结构和功能在神经发育过程中发生显着变化，并且可能受到物质使用的负面影响。在对一项比较酒精/大麻教育和 MI 的青少年物质使用临床试验数据进行二次分析时，我们评估了工作记忆与三个月治疗结果之间的关系，并假设干预条件与结果之间的关系将受到工作记忆的调节。通过目前使用酒精和/或大麻的青少年的不同样本（N = 153，64.7% 男性，70.6% 西班牙裔），我们研究了工作记忆基线测量与三个月随访中测量的酒精和大麻相关问题评分之间的关系。结果显示，较低的工作记忆分数仅与饮酒的较差治疗反应相关，并且仅在教育组内。在 MI 组中，工作记忆与治疗结果之间没有发现任何关系。结果表明，工作记忆能力问题可能会干扰青少年在标准教育干预措施中处理和实施酒精和大麻教育内容的能力。这些结果还表明，MI 可以在青少年的工作记忆功能范围内同样有效地实施。
Brief addiction treatments including motivational interviewing (MI) have shown promise with adolescents, but the factors that influence treatment efficacy in this population remain unknown. One candidate is working memory, the ability to hold a fact or thought in mind. This is relevant, as in therapy a client must maintain and manipulate ideas while working with a clinician. Working memory depends upon brain structures and functions that change markedly during neurodevelopment and that can be negatively impacted by substance use. In a secondary analysis of data from a clinical trial for adolescent substance use comparing alcohol/marijuana education and MI, we evaluated the relationship between working memory and three-month treatment-outcomes with the hypothesis that the relationship between intervention condition and outcome would be moderated by working memory. With a diverse sample of adolescents currently using alcohol and/or marijuana (N=153, 64.7% male, 70.6% Hispanic), we examined the relationship between baseline measures of working memory and alcohol and cannabis-related problem scores measured at the three-month follow-up. Results showed that lower working memory scores were associated with poorer treatment response only for alcohol use, and only within the education group. No relationship was found between working memory and treatment outcomes in the MI group. Results suggest that issues with working memory capacity may interfere with adolescents' ability to process and implement didactic alcohol and marijuana content in standard education interventions. These results also suggest that MI can be implemented equally effectively across the range of working memory functioning in youth.
登录
查看更多内容
影响因子：
8.2
作者：
Feldstein Ewing SW;Tapert SF;Molina BS
通讯作者：
Molina BS
影响因子：
16.2
作者：
Giedd, Jay N.;Rapoport, Judith L.
通讯作者：
Rapoport, Judith L.
影响因子：
3.9
作者：
Feldstein Ewing SW;Wray AM;Mead HK;Adams SK
通讯作者：
Adams SK
影响因子：
3.4
作者：
Ewing, Sarah W. Feldstein;McEachern, Amber D.;Filbey, Francesca M.
通讯作者：
Filbey, Francesca M.
影响因子：
7.6
作者：
Chen, Pan;Jacobson, Kristen C.
通讯作者：
Jacobson, Kristen C.