Effects of exercise training on gut hormone levels after a single bout of exercise in middle-aged Japanese women.
Effects of exercise training on gut hormone levels after a single bout of exercise in middle-aged Japanese women.
复制标题
DOI：
10.1186/2193-1801-2-83
复制
发表时间：
2013-12
期刊：
影响因子：
--
通讯作者：
Fujimoto S
中科院分区：
文献类型：
--
作者：
Ueda SY;Miyamoto T;Nakahara H;Shishido T;Usui T;Katsura Y;Yoshikawa T;Fujimoto S
这项研究的目的是调查12周的运动训练对日本中年妇女一次运动后肠道激素水平的影响。本研究招募了20名健康的中年妇女。在运动训练前后进行了几项测量，包括：体重和组成、峰值耗氧量（峰值VO2）、单次运动后的能量摄入、禁食和单次运动后肠道激素的释放。运动训练导致空腹饥饿素水平显著升高（从126.6±5.6增加到135.9±5.4 pmol/l, P < 0.01）， GLP-1（从0.54±0.04增加到0.55±0.03 pmol/ml）和PYY（从1.20±0.07增加到1.23±0.06 pmol/ml）空腹水平无显著变化。单次运动后运动训练后GLP-1水平显著高于运动前(曲线下面积；从238.4±65.2到286.5±51.2 pmol/ml x 120 min, P < 0.001)。运动后PYY时间课程的AUC有高于运动前课程的趋势（AUC从519.5±135.5增加到551.4±128.7 pmol/ml x 120 min, P = 0.06）。（δ） GLP-1 AUC的变化与体重（r = - 0.743, P < 0.001）、体重指数（r = - 0.732, P < 0.001）、体脂百分比（r = - 0.731, P < 0.001）、单次运动后能量摄入（r = - 0.649, P < 0.01）和峰值VO2 （r = 0.558, P < 0.05）的降低有显著相关。这些结果表明，运动训练产生负能量平衡的能力不仅直接取决于其对能量消耗的影响，还间接取决于其调节能量摄入的潜力。
The purpose of this study was to investigate the effects of 12 weeks of exercise training on gut hormone levels after a single bout of exercise in middle-aged Japanese women. Twenty healthy middle-aged women were recruited for this study. Several measurements were performed pre and post exercise training, including: body weight and composition, peak oxygen consumption (peak VO2), energy intake after the single bout of exercise, and the release of gut hormones with fasting and after the single bout of exercise. Exercise training resulted in significant increases in acylated ghrelin fasting levels (from 126.6 ± 5.6 to 135.9 ± 5.4 pmol/l, P < 0.01), with no significant changes in GLP-1 (from 0.54 ± 0.04 to 0.55 ± 0.03 pmol/ml) and PYY (from 1.20 ± 0.07 to 1.23 ± 0.06 pmol/ml) fasting levels. GLP-1 levels post exercise training after the single bout of exercise were significantly higher than those pre exercise training (areas under the curve (AUC); from 238.4 ± 65.2 to 286.5 ± 51.2 pmol/ml x 120 min, P < 0.001). There was a tendency for higher AUC for the time courses of PYY post exercise training than for those pre exercise training (AUC; from 519.5 ± 135.5 to 551.4 ± 128.7 pmol/ml x 120 min, P = 0.06). Changes in (delta) GLP-1 AUC were significantly correlated with decreases in body weight (r = −0.743, P < 0.001), body mass index (r = −0.732, P < 0.001), percent body fat (r = −0.731, P < 0.001), and energy intake after a single bout exercise (r = −0.649, P < 0.01) and increases in peak VO2 (r = 0.558, P < 0.05). These results suggest that the ability of exercise training to create a negative energy balance relies not only directly on its impact on energy expenditure, but also indirectly on its potential to modulate energy intake.
登录
查看更多内容
DOI：
10.1152/ajpregu.90706.2008
发表时间：
2009-01-01
影响因子：
2.8
作者：
Broom, David R.;Batterham, Rachel L.;Stensel, David J.
通讯作者：
Stensel, David J.
影响因子：
5.8
作者：
Konopko-Zubrzycka, M.;Baniukiewicz, A.;Dabrowski, A.
通讯作者：
Dabrowski, A.
影响因子：
7.1
作者：
Donnelly, JE;Kirk, EP;Johnson, SL
通讯作者：
Johnson, SL
影响因子：
6.9
作者：
Jones, Terry E.;Basilio, J. L.;Hickner, R. C.
通讯作者：
Hickner, R. C.
影响因子：
5.8
作者：
Leidy, HJ;Gardner, JK;Williams, NI
通讯作者：
Williams, NI