Lifecourse Activity Participation From Early, Mid, and Later Adulthood as Determinants of Cognitive Aging: The Lothian Birth Cohort 1921.
Lifecourse Activity Participation From Early, Mid, and Later Adulthood as Determinants of Cognitive Aging: The Lothian Birth Cohort 1921.
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DOI：
10.1093/geronb/gbw124
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发表时间：
2017-01
期刊：
影响因子：
--
通讯作者：
Deary IJ
中科院分区：
文献类型：
--
作者：
Gow AJ;Pattie A;Deary IJ
研究整个成年期活动参与的潜在敏感期，以减少认知能力下降，并确定在考虑认知能力终生稳定性后关联是否持续存在。 Lothian Birth Cohort 1921 是一项认知衰老的纵向研究。参与者出生于 1921 年，大多数在 11 岁时完成了心理能力测试。认知评估的平均年龄为 79 岁 (N = 550)、83 岁 (N = 321)、87 岁 (N = 235) 和 90 岁 (N = 129)。参与者提供了他们在青年期（20-35岁）、中期（40-55岁）、成年后期（60-75岁）以及79岁时参与活动的回顾性详细信息。利用潜在生长曲线模型检查了活动与老年认知能力水平和变化之间的关联。考虑到人口统计数据和儿童认知能力，中年时参与休闲活动与认知能力水平呈正相关（路径系数 = 0.32），而成年后期较高的体力活动与认知能力下降较少相关（0.27）。研究结果支持采用生命全程方法来确定认知衰老的决定因素；成年不同时期的休闲和身体活动可能会增强认知能力或减少认知能力下降。
To examine potential sensitive periods for activity participation across adulthood to reduce cognitive decline and to determine whether associations persist after accounting for the lifetime stability of cognitive ability. The Lothian Birth Cohort 1921 is a longitudinal study of cognitive aging. Participants were born in 1921 and most completed a mental ability test at the age of 11 years. Cognitive assessments were completed at mean ages 79 (N = 550), 83 (N = 321), 87 (N = 235), and 90 years (N = 129). Participants provided retrospective details of their activity participation for young (20–35 years), mid (40–55 years), and later adulthood (60–75 years), and contemporaneously at age 79. Associations between activity and the level of, and change in, cognitive ability in old age were examined with latent growth curve models. Accounting for demographics and childhood cognitive ability, engagement in leisure activities in midlife was positively associated with cognitive ability level (path coefficient = .32), whereas higher physical activity in later adulthood was associated with less cognitive decline (.27). The findings support a lifecourse approach in identifying determinants of cognitive aging; leisure and physical activity during different periods of adulthood may enhance cognitive abilities or reduce decline.
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