Prevalence and clinical profile of metabolic syndrome in longevity: study from Guangxi Zhuang Autonomous Region, China.
Prevalence and clinical profile of metabolic syndrome in longevity: study from Guangxi Zhuang Autonomous Region, China.
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长寿者代谢综合征的患病率和临床概况：中国广西壮族自治区的研究
DOI：
10.1186/s12877-017-0536-y
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发表时间：
2017-07-31
期刊：
影响因子：
4.1
通讯作者：
Yang Z
中科院分区：
文献类型：
--
作者：
He X;Zhang W;Pang G;Lv Y;Hu C;Yang Z
代谢综合征（MetS）是心血管疾病的危险因素，但在90岁和100岁的人群中的患病率很少报道。在此，我们调查了中国广西壮族自治区巴马壮族人群中90岁和百岁老人的MetS及其组分的患病率。在巴马地区26.98万名居民中，有881名90岁以上的老年人，我们的研究包括307名长寿参与者和486名当地年轻人（35-68岁）作为对照。MetS根据修订的国家胆固醇教育计划成人治疗组III（NCEP ATP III）标准定义。根据NCEP ATP III标准，长寿组MetS的总患病率估计为28.0%。最常见的代谢成分是血压升高（61.1%），其次是空腹血糖升高（39.1%）和低高密度脂蛋白胆固醇（低HDL-C）（28.0%）。女性代谢综合征和腹型肥胖的患病率（分别为33.6%和22.1%）高于男性（分别为19.8%和3.7%）（P范围<0.001 ~ 0.019）。与对照组相比，长寿组患者更容易出现两种或两种以上的代谢异常（P < 0.001），而很少出现零种或一种代谢异常（P < 0.001-0.020）。这项研究显示了中国广西壮族自治区长寿人群中MetS的患病率和临床特征。
Metabolic syndrome (MetS) was a risk factor for cardiovascular diseases, yet the prevalence of MetS among nonagenarians and centenarians was rarely reported. Here we investigated the prevalence of MetS and its components among nonagenarians and centenarians in our Zhuang population from Bama, Guangxi Zhuang Autonomous Region, China. In Bama area, there registered 881 individuals who lived more than 90 years old in 269,800 local residents and our study involved 307 long-lived participants and 486 local younger (35–68 years) persons, as controls. MetS was defined according to the revised National Cholesterol Education Program’s Adult Treatment Panel III (NCEP ATPIII) criteria. The overall prevalence estimates of MetS among longevity group were 28.0% based on NCEP ATPIII criteria. The most common metabolic component was elevated blood pressure (61.1%), followed by raised fasting glucose (39.1%) and low high-density lipoprotein cholesterol (low HDL-C) (28.0%). The prevalence of MetS and abdominal obesity in women (33.6% and 22.1% respectively) was higher than that of men (19.8% and 3.7% respectively) (Prange < .001–0.019). Compared with controls, long-lived individuals were more likely to have two or more metabolic abnormalities (Prange < 0.001), and less likely to have zero or one metabolic abnormality (Prange < 0.001–0.020). This study showed substantiality the prevalence and clinical profile of MetS in longevity population in Guangxi Zhuang Autonomous Region, China.
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影响因子：
4.8
作者：
Mazzotti DR;Guindalini C;Moraes WA;Andersen ML;Cendoroglo MS;Ramos LR;Tufik S
通讯作者：
Tufik S
影响因子：
9.8
作者：
Vinluan, Celeste M.;Zreikat, Halo H.;Levy, James R.;Cheang, Kai I.
通讯作者：
Cheang, Kai I.
影响因子：
9.3
作者：
Slagter SN;van Vliet-Ostaptchouk JV;Vonk JM;Boezen HM;Dullaart RP;Kobold AC;Feskens EJ;van Beek AP;van der Klauw MM;Wolffenbuttel BH
通讯作者：
Wolffenbuttel BH
改善血脂、舒张压和肾功能是家庭长寿的潜在因素：对 60 个中国百岁老人家庭的研究
影响因子：
4.6
作者：
He YH;Pu SY;Xiao FH;Chen XQ;Yan DJ;Liu YW;Lin R;Liao XP;Yu Q;Yang LQ;Yang XL;Ge MX;Li Y;Jiang JJ;Cai WW;Kong QP
通讯作者：
Kong QP
DOI：
10.1016/j.jamda.2012.10.001
发表时间：
2013-02-01
影响因子：
7.6
作者：
Luo, Li;Yang, Ming;Dong, Birong
通讯作者：
Dong, Birong