Transient decline in hippocampal theta activity during the acquisition process of the negative patterning task.
Transient decline in hippocampal theta activity during the acquisition process of the negative patterning task.
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DOI：
10.1371/journal.pone.0070756
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发表时间：
2013
期刊：
影响因子：
3.7
通讯作者：
Sakata S
中科院分区：
文献类型：
--
作者：
Sakimoto Y;Okada K;Takeda K;Sakata S
海马区的功能在负性模式的获得中很重要，但不是简单的辨别。本研究检测了大鼠在负性模式任务(A+，B+，AB-)的习得阶段(早、中、晚)的海马theta活动。结果表明，在负性模式任务的学习后期，海马theta活动开始一过性下降(无强化刺激呈现后持续500ms)。此外，在消极模式任务的后期，海马theta活动的这种短暂下降比在简单辨别任务中的要低。这种在任务习得后期的短暂下降可能与消极模式任务的学习过程有关，而与简单的辨别任务无关。我们认为，海马theta活性的短暂下降反映了在呈现针对负模式任务的复合刺激后的抑制性学习和/或反应抑制。
Hippocampal function is important in the acquisition of negative patterning but not of simple discrimination. This study examined rat hippocampal theta activity during the acquisition stages (early, middle, and late) of the negative patterning task (A+, B+, AB-). The results showed that hippocampal theta activity began to decline transiently (for 500 ms after non-reinforced stimulus presentation) during the late stage of learning in the negative patterning task. In addition, this transient decline in hippocampal theta activity in the late stage was lower in the negative patterning task than in the simple discrimination task. This transient decline during the late stage of task acquisition may be related to a learning process distinctive of the negative patterning task but not the simple discrimination task. We propose that the transient decline of hippocampal theta activity reflects inhibitory learning and/or response inhibition after the presentation of a compound stimulus specific to the negative patterning task.
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影响因子：
2.9
作者：
ALLEN, CN;CRAWFORD, IL
通讯作者：
CRAWFORD, IL
影响因子：
2.7
作者：
SUTHERLAND, RJ;MCDONALD, RJ
通讯作者：
MCDONALD, RJ
DOI：
10.1016/s0091-6773(73)80041-0
发表时间：
1973-01-01
期刊：
BEHAVIORAL BIOLOGY
影响因子：
--
作者：
WHISHAW, IQ;VANDERWOLF, CH
通讯作者：
VANDERWOLF, CH
影响因子：
3.8
作者：
Olvera-Cortés, E;Cervantes, M;González-Burgos, I
通讯作者：
González-Burgos, I
DOI：
10.1016/0013-4694(62)90052-4
发表时间：
1962-01-01
期刊：
ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY
影响因子：
--
作者：
SADOWSKI, B;LONGO, VG
通讯作者：
LONGO, VG