Effect of age on the association between waist-to-height ratio and incidence of cardiovascular disease: the Suita study.
Effect of age on the association between waist-to-height ratio and incidence of cardiovascular disease: the Suita study.
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DOI：
10.2188/jea.je20130004
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发表时间：
2013-09-05
影响因子：
4.7
通讯作者：
Miyamoto Y
中科院分区：
文献类型：
--
作者：
Tatsumi Y;Watanabe M;Kokubo Y;Nishimura K;Higashiyama A;Okamura T;Okayama A;Miyamoto Y
腰围/身高比(WHtR)已被证明是代谢综合征和心血管疾病(CVD)的有用筛查工具。我们调查了WHtR与不同年龄组心血管疾病发病率的关系。我们对没有心血管病史的日本成年人(2600名男性和2888名女性)进行了一项为期13.0年的队列研究。WHtR的计算方法为腰围(Cm)除以身高(Cm)。我们按性别和年龄组(30-49岁，50-69岁，≥70岁)对参与者进行分层。使用COX比例风险模型，我们计算了50至69岁和70岁或以上参与者的心血管疾病风险比(HR)和95%的CI与WHtR四分位数的关系。与后四分位数相比，年龄在50-69岁之间的男性患心血管疾病和冠心病的风险显著增加，其相对危险度(95%CI)分别为1.82(1.13-2.92)和2.42(1.15-5.12)。年龄在50到69岁之间的女性中风风险显著增加(HR，2.43；95%CI，1.01-5.85)。在70岁或70岁以上的男性或女性中没有观察到显著的结果。似然比检验显示，在50~69岁男性中，WHtR的预测值大于WC。WHtR和心血管疾病风险之间的关联在不同年龄组之间有所不同。WHTR在识别日本中年人心血管疾病风险较高方面是有用的，并且比WC更好地预测心血管疾病，尤其是在男性。
Waist-to-height ratio (WHtR) has been shown to be a useful screening tool for metabolic syndrome and cardiovascular disease (CVD). We investigated the association of WHtR with CVD incidence by age group. We conducted a 13.0-year cohort study of Japanese adults (2600 men and 2888 women) with no history of CVD. WHtR was calculated as waist circumference (cm) (WC) divided by height (cm). We stratified participants by sex and age group (30–49, 50–69, ≥70 years). Using the Cox proportional hazards model, we calculated hazard ratios (HRs) and 95% CIs for CVD in relation to WHtR quartile for participants aged 50 to 69 years and 70 years or older. Men aged 50 to 69 years in the highest quartile had significantly increased risks of CVD and coronary heart disease as compared with the lowest quartile; the HRs (95% CI) were 1.82 (1.13–2.92) and 2.42 (1.15–5.12), respectively. Women aged 50 to 69 years in the highest quartile had a significantly increased risk of stroke (HR, 2.43; 95% CI, 1.01–5.85). No significant results were observed in men or women aged 70 years or older. The likelihood ratio test showed that the predictive value of WHtR was greater than that of WC among men aged 50 to 69 years. The association between WHtR and CVD risk differed among age groups. WHtR was useful in identifying middle-aged Japanese at higher risk of CVD and was a better predictor than WC of CVD, especially in men.
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影响因子：
16.2
作者：
Schneider DJ;Sobel BE
通讯作者：
Sobel BE
影响因子：
3.3
作者：
Kashihara, Hidetoshi;Lee, Jung Su;Akabayashi, Akira
通讯作者：
Akabayashi, Akira
影响因子：
37.8
作者：
Alberti, K. G. M. M.;Eckel, Robert H.;Smith, Sidney C., Jr.
通讯作者：
Smith, Sidney C., Jr.
DOI：
10.1097/ede.0b013e31819f38f1
发表时间：
2009-05
期刊：
Epidemiology (Cambridge, Mass.)
影响因子：
--
作者：
Page JH;Rexrode KM;Hu F;Albert CM;Chae CU;Manson JE
通讯作者：
Manson JE
影响因子：
8.3
作者：
Furukawa, Yoko;Kokubo, Yoshihiro;Date, Chigusa
通讯作者：
Date, Chigusa