Deadly COVID-19 among the elderly: Innate immune memory helping those most in need.
Deadly COVID-19 among the elderly: Innate immune memory helping those most in need.
复制标题
DOI:
10.1016/j.medj.2021.02.004
复制
发表时间:
2021-04-09
期刊:
影响因子:
--
通讯作者:
Netea MG
中科院分区:
文献类型:
--
作者:
Sohrabi Y;Reinecke H;Joosten LAB;Netea MG
Age is a key risk factor associated with the severity of symptoms caused by SARS-CoV-2, and there is an urgent need to reduce COVID-19 morbidity and mortality in elderly individuals. We discuss evidence suggesting that trained immunity elicited by BCG vaccination may improve immune responses and can serve as a strategy to combat COVID-19 in this population. Age is a key risk factor associated with the severity of symptoms caused by SARS-CoV-2, and there is an urgent need to reduce COVID-19 morbidity and mortality in elderly individuals. We discuss evidence suggesting that trained immunity elicited by BCG vaccination may improve immune responses and can serve as a strategy to combat COVID-19 in this population.
登录
查看更多内容
影响因子:
7.8
作者:
Santesmasses D;Castro JP;Zenin AA;Shindyapina AV;Gerashchenko MV;Zhang B;Kerepesi C;Yim SH;Fedichev PO;Gladyshev VN
通讯作者:
Gladyshev VN
DOI:
10.1073/pnas.2012358117
发表时间:
2020-10-06
影响因子:
11.1
作者:
Steinman JB;Lum FM;Ho PP;Kaminski N;Steinman L
通讯作者:
Steinman L
影响因子:
8.8
作者:
Quinn, Kylie M.;Fox, Annette;La Gruta, Nicole L.
通讯作者:
La Gruta, Nicole L.
影响因子:
9.8
作者:
Glynn JR;Moss PAH
通讯作者:
Moss PAH
DOI:
10.1016/j.clim.2014.10.005
发表时间:
2014-12
期刊:
Clinical immunology (Orlando, Fla.)
影响因子:
--
作者:
Kleinnijenhuis J;Quintin J;Preijers F;Joosten LA;Jacobs C;Xavier RJ;van der Meer JW;van Crevel R;Netea MG
通讯作者:
Netea MG