Alcohol consumption and risk of renal cell cancer: the NIH-AARP diet and health study.

Alcohol consumption and risk of renal cell cancer: the NIH-AARP diet and health study.
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DOI:
10.1038/sj.bjc.6606089
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发表时间:
2011-02-01
影响因子:
8.8
通讯作者:
--
中科院分区:
医学1区
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--
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中度至大量饮酒(每天>15克)对肾细胞癌(RCC)风险的影响尚不清楚。 NIH-AARP 饮食与健康研究(n=49 2187,1814 例)检查了饮酒与 RCC 之间的关系。与每天饮酒量 >0 至 <5 克相比,男性每天饮酒 15 至 <30 克和 30 克的多变量相对风险(95% 置信区间)分别为 0.75 (0.63–0.90) 和 0.71 (0.59–0.85),男性为 0.67 (0.42–1.07) 和 0.43女性分别为 (0.22–0.84)。饮酒量与 RCC 呈剂量反应负相关。这种负相关性可能会扩大到每天 30 克的酒精摄入量。
The effect of moderate to heavy drinking (>15 g per day) on renal cell cancer (RCC) risk is unclear. The relationship between alcohol consumption and RCC was examined in the NIH-AARP Diet and Health Study (n=49 2187, 1814 cases). Compared with >0 to <5 g per day of alcohol consumption, the multivariate relative risk (95% confidence intervals) for 15 to <30 and ⩾30 g per day was, 0.75 (0.63–0.90) and 0.71 (0.59–0.85), respectively, in men and 0.67 (0.42–1.07) and 0.43 (0.22–0.84), respectively, in women. Alcohol consumption was inversely associated with RCC in a dose–response manner. The inverse association may be extended to ⩾30 g per day of alcohol intake.
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