Introduction to Single-Cell DNA Methylation Profiling Methods.
Introduction to Single-Cell DNA Methylation Profiling Methods.
复制标题
DOI:
10.3390/biom11071013
复制
发表时间:
2021-07-10
期刊:
影响因子:
5.5
通讯作者:
Bang D
中科院分区:
文献类型:
--
作者:
Ahn J;Heo S;Lee J;Bang D
DNA methylation is an epigenetic mechanism that is related to mammalian cellular differentiation, gene expression regulation, and disease. In several studies, DNA methylation has been identified as an effective marker to identify differences between cells. In this review, we introduce single-cell DNA-methylation profiling methods, including experimental strategies and approaches to computational data analysis. Furthermore, the blind spots of the basic analysis and recent alternatives are briefly described. In addition, we introduce well-known applications and discuss future development.
登录
查看更多内容
影响因子:
46.9
作者:
Ball, Madeleine P.;Li, Jin Billy;Gao, Yuan;Lee, Je-Hyuk;LeProust, Emily M.;Park, In-Hyun;Xie, Bin;Daley, George Q.;Church, George M.
通讯作者:
Church, George M.
影响因子:
13.6
作者:
Avanzini S;Kurtz DM;Chabon JJ;Moding EJ;Hori SS;Gambhir SS;Alizadeh AA;Diehn M;Reiter JG
通讯作者:
Reiter JG
影响因子:
48
作者:
Angermueller C;Clark SJ;Lee HJ;Macaulay IC;Teng MJ;Hu TX;Krueger F;Smallwood S;Ponting CP;Voet T;Kelsey G;Stegle O;Reik W
通讯作者:
Reik W
影响因子:
5.2
作者:
Chuang, Yu-Hsuan;Quach, Austin;Ritz, Beate
通讯作者:
Ritz, Beate
影响因子:
3.7
作者:
Doherty R;Couldrey C
通讯作者:
Couldrey C