Drug Use Among Adolescents and Young Adults with Unsuppressed HIV Who Use Alcohol: Identifying Patterns of Comorbid Drug Use and Associations with Mental Health.

Drug Use Among Adolescents and Young Adults with Unsuppressed HIV Who Use Alcohol: Identifying Patterns of Comorbid Drug Use and Associations with Mental Health.
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DOI:
10.1007/s10461-020-02848-8
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发表时间:
2020-10
期刊:
影响因子:
4.4
通讯作者:
Naar, Sylvie
Naar, Sylvie
中科院分区:
医学2区
文献类型:
--
作者:
Starks, Tyrel J.;MacDonell, Karen Kolmodin;Pennar, Amy L.;Dinaj-Koci, Veronica;Millar, Brett M.;Naar, Sylvie

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感染艾滋病毒的青年(16-24岁)酗酒和吸毒的风险较高。对老年人的研究已经确定了多种物质使用的模式或概况,这些模式或概况与心理健康和抗逆转录病毒治疗(ART)依从性有差异。目前还没有关于YLWH的研究探讨过这种模式。2014年11月至2017年8月期间,在美国城市地区的五个青少年试验网络诊所招募了179名报告ART不依从和饮酒的YLWH样本。参与者完成了酒精吸烟和物质参与筛选测试(ASSIST),以评估物质使用参与评分和简要症状清单。潜在特征分析确定了三种物质使用模式:最低限度的非法药物使用(15.1%),仅大麻(56.4%)和全球多种物质使用(28.5%)。与最低限度非法药物使用组相比,全球多种药物使用者经历了更多的心理健康问题。药物使用与酒精的共同发生在这些YLWH中很常见-所有这些人都报告了ART依从性问题-表明能够解决多种物质使用而不仅仅是酒精的干预措施的重要性。
Youth living with HIV (YLWH; aged 16–24) are at elevated risk of alcohol and drug use. Studies in older populations have identified patterns or profiles of multiple substance use differentially associated with mental health and anti-retroviral therapy (ART) adherence. No studies of YLWH have yet examined such patterns. A sample of 179 YLWH, reporting ART non-adherence and alcohol use, were recruited at five Adolescent Trials Network clinics in urban areas of the US between November 2014 and August 2017. Participants completed the Alcohol Smoking and Substance Involvement Screening Test (ASSIST) to assess substance use involvement scores, and the Brief Symptom Inventory. Latent Profile Analysis identified three substance use patterns: minimal illicit drug use (15.1%), cannabis only (56.4%), and global polysubstance use (28.5%). Global polysubstance users experienced more mental health problems compared to the minimal illicit drug use group. The co-occurrence of drug use with alcohol was common among these YLWH – all of whom reported ART adherence problems – indicating the importance of interventions capable of addressing multiple substance use rather than alcohol alone.
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