Association between maternal antenatal depression and infant development: a hospital-based prospective cohort study
Association between maternal antenatal depression and infant development: a hospital-based prospective cohort study
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母亲产前抑郁症与婴儿发育之间的关联：一项以医院为基础的前瞻性队列研究
DOI：
10.1007/s12199-013-0353-7
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发表时间：
2014
期刊：
影响因子：
--
通讯作者：
Kishi R
中科院分区：
文献类型：
--
作者：
Otake Y;Nakajima S;Uno A;Kato S;Sasaki S;Yoshioka E;Ikeno T;Kishi R
目的探讨产前抑郁症和婴儿发育之间的关联控制混杂factors.MethodsA医院为基础的前瞻性队列研究（北海道研究环境和儿童健康）之间进行了2002年7月和2005年10月在日本札幌。在研究期间，在札幌东邦医院分娩并同意抑郁症临床评估的309名母亲中，有154对母婴符合分析条件。使用爱丁堡产后抑郁量表（EPDS）在第二和第三个三个月之间评估产后抑郁症，并在6个月时使用贝利婴儿发育量表II（BSID-II）评估婴儿发育。潜在混杂因素的数据，包括社会经济地位，出生并发症，产后抑郁症和儿童保育环境，从医疗记录和自填问卷中获得。进行单变量和多变量分析，其中EPDS评分作为一个独立变量和BSID-II评分作为一个因变量，调整confronters.ResultsAlthough产前EPDS评分往往是相关的BSID-II评分在单变量分析，这种相关性在多变量分析中丢失。然而，基于一系列的线性回归分析，发现产前抑郁症与较短的胎龄显著相关（β= −0.25，95%置信区间（CI）[−1.20，−0.17]），较短的胎龄与较低的BSID-II显著相关结论孕龄是母亲产前抑郁与婴儿发育关系的重要混杂因素。婴儿发育延迟可能与母亲在怀孕期间抑郁导致的妊娠期缩短有关。
ObjectiveTo examine the association between antenatal depression and infant development after controlling for confounding factors.MethodsA hospital-based prospective cohort study (Hokkaido Study on Environment and Children’s Health) was conducted between July 2002 and October 2005 in Sapporo, Japan. Of 309 mothers who delivered at Sapporo Toho Hospital during the study period and who agreed with the clinical assessment of depression, 154 mother–infant pairs were eligible for analysis. Antenatal depression was assessed between the second and third trimesters using the Edinburgh Postnatal Depression Scale (EPDS), and infant development was assessed at 6 months by the Bayley Scales of Infant Development II (BSID-II). Data on potential confounders, including socioeconomic status, birth complications, postnatal depression and child care environment, were obtained from medical records and self-administered questionnaires. Univariable and multivariable analyses were conducted in which the EPDS score was entered as an independent variable and the BSID-II scores as a dependent variable, adjusting for confounders.ResultsAlthough the antenatal EPDS score tended to be related to the BSID-II score in the univariable analysis, this correlation was lost in the multivariable analysis. However, based on a series of linear regression analyses, antenatal depression was found to be significantly related to shorter gestational age (β= −0.25, 95 % confidence interval (CI) [−1.20, −0.17]), and shorter gestational age was significantly related to a lower BSID-II (mental development) score (β= 0.23, 95 % CI [0.00, 0.00]).ConclusionsGestational age is an important confounder in the association between maternal antenatal depression and infant development. A delay in infant development may be related to a shorter gestational period caused by maternal depression during pregnancy.
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DOI：
--
发表时间：
2020
期刊：
--
影响因子：
--
作者：
J. Seckl
通讯作者：
J. Seckl
DOI：
10.1097/chi.0b013e31817eec80
发表时间：
2008-09-01
影响因子：
13.3
作者：
Laplante, David P.;Brunet, Alain;King, Suzanne
通讯作者：
King, Suzanne
DOI：
10.1016/s0002-9378(99)70708-8
发表时间：
1999-01-01
影响因子：
9.8
作者：
Majzoub, JA;Karalis, KP
通讯作者：
Karalis, KP
日本围产期抑郁症的多中心前瞻性研究：产前和产后抑郁症的发生率和相关性
DOI：
--
发表时间：
2006
期刊：
Archives of Women's Mental Health (In press)
影响因子：
--
作者：
Kitamara T;Yoshida K;Okano T;et al.
通讯作者：
et al.
影响因子：
2.5
作者：
Diego, Miguel A.;Field, Tiffany;Hernandez-Reif, Maria;Schanberg, Saul;Kuhn, Cynthia;Gonzalez-Quintero, Victor Hugo
通讯作者：
Gonzalez-Quintero, Victor Hugo