Behavioural and neurochemical responses to acute, subchronic, and chronic intermittent stressors in relation to depression: Contribution of 5-HT, CRH and BDNF to the depressive phenotype

对与抑郁相关的急性、亚慢性和慢性间歇性应激源的行为和神经化学反应：5-HT、CRH 和 BDNF 对抑郁表型的贡献

• 批准号: 199509
• 负责人: Anisman Hymie
• 金额: $ 59.41万
• 依托单位: Carleton University (Ottawa)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2010
• 资助国家: 加拿大
• 起止时间: 2010-03-01 至 2015-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=199509&lang=en
• 关键词: Anxiety; Bdnf; Crh And Crh Receptors; Depression; Genetic; Serotonin

Stressful events have been associated with several illnesses, such as anxiety and major depressive disorder. These adverse outcomes may represent a failure of adaptive biological processes when stressor experiences are prolonged and occur on an intermitte

应激事件与几种疾病有关，如焦虑和严重抑郁障碍。当应激源经历时间延长并间歇性发生时，这些不良后果可能代表适应性生物过程的失败。