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Molecular Characterization of P4-ATPases and Their Role in Membrane Lipid Asymmetry, Photoreceptor Cell Structure and Function, and Retinal Degenerative Diseases.

Molecular Characterization of P4-ATPases and Their Role in Membrane Lipid Asymmetry, Photoreceptor Cell Structure and Function, and Retinal Degenerative Diseases.
P4-ATP酶的分子特征及其在膜脂不对称、感光细胞结构和功能以及视网膜退行性疾病中的作用。
批准号:
201522
负责人:
Molday Robert S
金额:
$49.42万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2010
资助国家:
加拿大
项目状态:
已结题
起止时间:
2010-03-01 至 2015-03-01

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中文摘要
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英文摘要
Phospholipids are known to be asymmetrical distributed across biological membranes. This asymmetry plays a crucial role for a wide variety of cellular processes including membrane fusion and vesicle trafficking, aging, cell survival, phagocytosis and gene
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High Resolution Structure of Human ABCA4, an ATP-binding Cassette (ABC) Lipid Importer Associated with Inherited Retinal Degenerative Diseases
  • 批准号:
    433524
  • 项目类别:
    Operating Grants
  • 资助金额:
    $66.88万
  • 财政年份:
    2020
  • 负责人:
    Molday Robert S
  • 依托单位:
Molecular Mechanisms and Therapeutic Approaches to Stargardt Macular Degeneration
  • 批准号:
    343169
  • 项目类别:
    Operating Grants
  • 资助金额:
    $79.36万
  • 财政年份:
    2016
  • 负责人:
    Molday Robert S
  • 依托单位:
Canada Research Chair Tier 1
  • 批准号:
    315434
  • 项目类别:
  • 资助金额:
    $101.99万
  • 财政年份:
    2014
  • 负责人:
    Molday Robert S
  • 依托单位:
海外基金