Multiscale stochastic modelling of tumour robustness

该项目将开发系统生物学的尖端建模方法和创新的实验技术，以研究肿瘤启动和进展的原则，这是国家研究重点前沿技术的核心，用于建设和改造澳大利亚工业。主要结果将是解释肿瘤发生、癌症疾病进展和治疗耐药性演变的基本新范式。在这项研究中获得的深刻见解有可能成为癌症疾病的最佳治疗策略，这与促进和保持澳大利亚人的健康密切相关。

This project will develop cutting-edge modelling methodologies of systems biology and innovative experimental techniques to investigate the principles of tumour initiation and progression, which lay at the heart of the national research priority Frontier Technologies for Building and Transforming Australian Industries. The primary outcome will be fundamental new paradigms explaining tumour initiation, cancer disease progression and the evolution of therapy resistance. The deep insights gained in this research have the potential for the optimal treatment strategies of cancer diseases, which is strongly relevant to promoting and maintaining good health for Australians.