"Metabolic control of integrin membrane traffic by AMPK drives breast cancer growth, survival, migration and invasion."

“AMPK 对整合素膜运输的代谢控制可促进乳腺癌的生长、存活、迁移和侵袭。”

• 批准号: 429008
• 负责人: Orofiamma Laura A
• 金额: $ 1.27万
• 依托单位: Toronto Metropolitan University
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2019
• 资助国家: 加拿大
• 起止时间: 2019-12-01 至 2020-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=429008&lang=en
• 关键词: Ampk; Arf6; Arfgap3; Cancer; Invasion; Metabolic Stress; Metabolism; Metastasis; Migration; Organoid

"Cancer cells exhibit large differences in metabolism compared to healthy cells, in particular, how certain nutrients are used as fuel by cancer cells. Cancer cells not only have unique demands for specific nutrients, but are exposed to a unique environme

“与健康细胞相比，癌细胞在新陈代谢方面表现出很大的差异，特别是某些营养物质如何被癌细胞用作燃料。癌细胞不仅对特定的营养物质有独特的需求，而且暴露在独特的环境中