The effects of TCR affinity on the quality and persistence of peripheral T cell tolerance

TCR亲和力对外周T细胞耐受的质量和持久性的影响

• 批准号: 439855
• 负责人: Valbon Fernandes Garcia Stefanie
• 金额: $ 7.65万
• 依托单位: Universit de Montral
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2020
• 资助国家: 加拿大
• 起止时间: 2020-11-01 至 2023-11-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=439855&lang=en
• 关键词: Autoimmunity; Flow Cytometry; Self-Reactive Tcr; T Cell Tolerance; Tcr Affinity

T cells are specialized immune cells that protect us against infection and cancer. These cells express a molecule (known as the T cell receptor) that recognizes pieces of foreign or abnormal proteins that are displayed on the surface of infected or cancer

T细胞是专门的免疫细胞，保护我们免受感染和癌症。这些细胞表达一种分子（称为T细胞受体），该分子识别感染或癌症表面上显示的外源或异常蛋白质片段。