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Flow Cytometry Core

流式细胞术核心

基本信息

批准号：
10630389
负责人：
MARK S DOONER
金额：
$ 21.32万
依托单位：
RHODE ISLAND HOSPITAL
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-07-01 至 2028-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10630389
关键词：
Advisory Services Aging Area Basic Science Biomedical Research Buffers Cell Separation Cells Centers of Research Excellence Clinical Clinical Research Collaborations Communities Core Facility Cytometry Data Collection Data Storage and Retrieval Dedications Discipline Experimental Designs Flow Cytometry Goals Growth Health Personnel Hospitals Human Resources Inductively Coupled Plasma Mass Spectrometry Institution Lasers Longevity Mass Spectrum Analysis Phase Phenotype Pilot Projects Population Positioning Attribute Property Research Research Activity Research Personnel Research Project Grants Resources Rhode Island Role Services Sodium Chloride Solid Source Suspensions System Techniques Technology Tissues Universities instrumentation laser cell sorter particle programs single cell analysis stem cells success time of flight mass spectrometry tool

项目摘要

Flow Cytometry Core Abstract The Flow Cytometry Core was initially formed to fulfill the flow cytometry needs of the projects and pilot projects of the original COBRE Phase I application. The Core provided expertise in stem cell and rare cell separations, cell sorting and cell phenotyping analysis, by making available, state-of-the-art instrumentation for the flow cytometry needs of the COBRE investigators as well as the clinical and basic research community in Rhode Island. Today, the Flow Cytometry Core continues to fulfill this critical role and supports a multitude of research programs, projects and diverse research areas at Rhode Island Hospital and different institutions in the state of Rhode Island. It remains heavily utilized, partially due to the strong support and success of the COBRE’s here in Rhode Island but also the strategic importance and basic relevance that flow cytometry brings to the research community at large. This is the only research flow cytometry core facility at Rhode Island Hospital and the only research flow cytometry core facility that offers access to a 5-laser sorter, 4-laser analyzer and a mass cytometer in the state. Flow cytometry remains an extremely useful tool for researchers over many different research disciplines. The institution has been generous with its administrative and fiscal support of the Flow Cytometry Core. Notably, this year Rhode Island Hospital has purchased and installed, a Fluidigm Helios CyTOF system, that is now available through the COBRE Flow Cytometry Core. This CyTOF platform will be utilized by clinical and basic researchers in the State of Rhode Island and shows a high level of support and dedication to the success of the proposed COBRE Flow Cytometry Core. With the new state-of-the-art instrumentation and Core expansion plan directed towards expanding inclusion of clinical research projects, our Core is well positioned to continue its growth and achieve long-term financial sustainability.

流式细胞仪核心