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Deciphering the metabolic and tumorigenic functions of STAT1 in mutant KRAS cancer.

Deciphering the metabolic and tumorigenic functions of STAT1 in mutant KRAS cancer.
破译 STAT1 在突变型 KRAS 癌症中的代谢和致瘤功能。
批准号：
444406
负责人：
Koromilas Antonis E
金额：
$67.99万
依托单位：
CIUSSS de Centre-Ouest-de-l'Ile-de-Montral-Jewish General
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2021
资助国家：
加拿大
项目状态：
未结题
起止时间：
2021-04-01 至 2026-04-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=444406&lang=en
关键词：
Anti-Tumor Drugs Gene Expression Kras Oncogene Protein Phosphorylation Sterol And Lipid Metabolism Transcription Factor Stat1 Transgenic Mice Tumor Formation

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英文摘要
Mutations in KRAS gene are found in deadly forms of cancer like colorectal, lung and pancreatic cancers. Mutant KRAS gene produces a protein, which has the capacity to enhance the proliferation of cells and promote tumor growth. Also, mutant KRAS rewires
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