Preclinical study of deep brain stimulation of the nucleus accumbens for the treatment of severe self-injurious behaviours associated with Autism Spectrum Disorder

伏隔核深部脑刺激治疗与自闭症谱系障碍相关的严重自残行为的临床前研究

• 批准号: 466667
• 负责人: Zhang Ke Xin
• 金额: $ 1.27万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-12-01 至 2022-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=466667&lang=en
• 关键词: Autism; Deep Brain Stimulation; Imaging; Mouse; Neuroscience; Neurosurgery; Nucleus Accumbens; Self-Injurious Behaviour

Children with Autism Spectrum Disorder (ASD) often manifest self-injurious behaviour (SIB) that may be exceptionally challenging to treat. Severe SIB is associated with physical injury, distress, repeated hospitalizations and reduced quality of life for c

自闭症谱系障碍（ASD）儿童经常表现出自我伤害行为（SIB），这可能是非常具有挑战性的治疗。严重的SIB与身体伤害，痛苦，反复住院和生活质量下降有关。