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Immunogenetic influences on the clinical phenotype of ankylosing spondylitis

Immunogenetic influences on the clinical phenotype of ankylosing spondylitis
免疫遗传学对强直性脊柱炎临床表型的影响
批准号:
197231
负责人:
Haroon Nigil
金额:
$7.29万
依托单位:
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2009
资助国家:
加拿大
项目状态:
已结题
起止时间:
2009-11-01 至 2011-11-01

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中文摘要
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英文摘要
Background: Patient with ankylosing spondylitis (AS) suffer from severe pain, systemic symptoms and progressive abnormal posture leading to work loss and decreased quality of life. HLA-B27 remains the gene with the strongest disease association. Recently,
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会议论文
HIF1-alpha interacts with MIF to drive inflammation and new bone formation in spondyloarthritis
  • 批准号:
    445586
  • 项目类别:
    Operating Grants
  • 资助金额:
    $48.49万
  • 财政年份:
    2021
  • 负责人:
    Haroon Nigil
  • 依托单位:
Therapeutic Targeting of MIF in a Spondyloarthritis Mouse Model
  • 批准号:
    381460
  • 项目类别:
    Operating Grants
  • 资助金额:
    $22.01万
  • 财政年份:
    2018
  • 负责人:
    Haroon Nigil
  • 依托单位:
Human Immunology Spondyloarthritis Team (HUMISPOT) studying immunopathogenesis, disease heterogeneity and drug discovery in spondyloarthritis
  • 批准号:
    395724
  • 项目类别:
    Operating Grants
  • 资助金额:
    $1.46万
  • 财政年份:
    2018
  • 负责人:
    Haroon Nigil
  • 依托单位:
Personalized medicine for ankylosing spondylitis
  • 批准号:
    365355
  • 项目类别:
    Operating Grants
  • 资助金额:
    $14.57万
  • 财政年份:
    2017
  • 负责人:
    Haroon Nigil
  • 依托单位:
海外基金