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Definitive treatment of AS by blocking Macrophage Migration Inhibitory Factor (MIF)

Definitive treatment of AS by blocking Macrophage Migration Inhibitory Factor (MIF)
通过阻断巨噬细胞迁移抑制因子 (MIF) 彻底治疗 AS
批准号:
351879
负责人:
Haroon Nigil
金额:
$7.29万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2016
资助国家:
加拿大
项目状态:
已结题
起止时间:
2016-04-01 至 2017-04-01

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中文摘要
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英文摘要
Background: Back pain is one of the two top causes of disability according to the Centre for Disease Control and affects 20% of Canadians. Ankylosing spondylitis (AS) is the most common inflammatory arthritis causing back pain. AS affects young men and w
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HIF1-alpha interacts with MIF to drive inflammation and new bone formation in spondyloarthritis
  • 批准号:
    445586
  • 项目类别:
    Operating Grants
  • 资助金额:
    $48.49万
  • 财政年份:
    2021
  • 负责人:
    Haroon Nigil
  • 依托单位:
Therapeutic Targeting of MIF in a Spondyloarthritis Mouse Model
  • 批准号:
    381460
  • 项目类别:
    Operating Grants
  • 资助金额:
    $22.01万
  • 财政年份:
    2018
  • 负责人:
    Haroon Nigil
  • 依托单位:
Human Immunology Spondyloarthritis Team (HUMISPOT) studying immunopathogenesis, disease heterogeneity and drug discovery in spondyloarthritis
  • 批准号:
    395724
  • 项目类别:
    Operating Grants
  • 资助金额:
    $1.46万
  • 财政年份:
    2018
  • 负责人:
    Haroon Nigil
  • 依托单位:
Personalized medicine for ankylosing spondylitis
  • 批准号:
    365355
  • 项目类别:
    Operating Grants
  • 资助金额:
    $14.57万
  • 财政年份:
    2017
  • 负责人:
    Haroon Nigil
  • 依托单位:
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