Immunogenetic influences on the clinical phenotype of Ankylosing Spondylitis
免疫遗传学对强直性脊柱炎临床表型的影响
基本信息
- 批准号:194035
- 负责人:
- 金额:$ 8.01万
- 依托单位:
- 依托单位国家:加拿大
- 项目类别:Fellowship Programs
- 财政年份:2009
- 资助国家:加拿大
- 起止时间:2009-10-01 至 2011-10-01
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Background: Patient with ankylosing spondylitis (AS) suffer from severe pain, systemic symptoms and progressive abnormal posture leading to work loss and decreased quality of life. HLA-B27 remains the gene with the strongest disease association. Recently,
背景资料:强直性脊柱炎(AS)患者疼痛剧烈,全身症状和进行性姿势异常,导致工作丧失和生活质量下降。HLA-B27仍然是与疾病相关性最强的基因。最近,
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Haroon Nigil其他文献
Haroon Nigil的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Haroon Nigil', 18)}}的其他基金
HIF1-alpha interacts with MIF to drive inflammation and new bone formation in spondyloarthritis
HIF1-α 与 MIF 相互作用,促进脊柱关节炎中的炎症和新骨形成
- 批准号:
445586 - 财政年份:2021
- 资助金额:
$ 8.01万 - 项目类别:
Operating Grants
Therapeutic Targeting of MIF in a Spondyloarthritis Mouse Model
MIF 在脊柱关节炎小鼠模型中的治疗靶向
- 批准号:
381460 - 财政年份:2018
- 资助金额:
$ 8.01万 - 项目类别:
Operating Grants
Human Immunology Spondyloarthritis Team (HUMISPOT) studying immunopathogenesis, disease heterogeneity and drug discovery in spondyloarthritis
人类免疫学脊柱关节炎团队 (HUMISPOT) 研究脊柱关节炎的免疫发病机制、疾病异质性和药物发现
- 批准号:
395724 - 财政年份:2018
- 资助金额:
$ 8.01万 - 项目类别:
Operating Grants
Personalized medicine for ankylosing spondylitis
强直性脊柱炎个体化用药
- 批准号:
365355 - 财政年份:2017
- 资助金额:
$ 8.01万 - 项目类别:
Operating Grants
Definitive treatment of AS by blocking Macrophage Migration Inhibitory Factor (MIF)
通过阻断巨噬细胞迁移抑制因子 (MIF) 彻底治疗 AS
- 批准号:
351879 - 财政年份:2016
- 资助金额:
$ 8.01万 - 项目类别:
Operating Grants
Studies on the complex interaction of autophagy with endoplamic reticulum aminopeptidase 1, unfolded protein response and natural killer cell response in the pathogenesis of ankylosing spondylitis
强直性脊柱炎发病机制中自噬与内质网氨肽酶1、未折叠蛋白反应和自然杀伤细胞反应复杂相互作用的研究
- 批准号:
310329 - 财政年份:2014
- 资助金额:
$ 8.01万 - 项目类别:
Operating Grants
Immunogenetic influences on the clinical phenotype of ankylosing spondylitis
免疫遗传学对强直性脊柱炎临床表型的影响
- 批准号:
197231 - 财政年份:2009
- 资助金额:
$ 8.01万 - 项目类别:
Studentship Programs
相似海外基金
Defining MHC class I restricted antigen presentation to CD8 T cells in experimental AD and Tauopathy - Supplement
定义实验性 AD 和 Tau 病中 MHC I 类限制性抗原呈递至 CD8 T 细胞 - 补充
- 批准号:
10836880 - 财政年份:2023
- 资助金额:
$ 8.01万 - 项目类别:
Targeting MAL2-mediated endocytosis to enhance tumor cell antigen presentation
靶向 MAL2 介导的内吞作用以增强肿瘤细胞抗原呈递
- 批准号:
10734324 - 财政年份:2023
- 资助金额:
$ 8.01万 - 项目类别:
Antigen presentation to the adaptive immune system in the choroid contributes to ocular autoimmune disease
脉络膜中的适应性免疫系统的抗原呈递导致眼部自身免疫性疾病
- 批准号:
10740465 - 财政年份:2023
- 资助金额:
$ 8.01万 - 项目类别:
Investigation of Target Protein Degradation and Its Effect on Enhancing Cancer-Specific Antigen Presentation by Quantitative Mass Spectrometry
通过定量质谱研究靶蛋白降解及其对增强癌症特异性抗原呈递的影响
- 批准号:
23K04971 - 财政年份:2023
- 资助金额:
$ 8.01万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Promoting cancer cells' antigen presentation for serving as better targets for T cell immunotherapy
促进癌细胞的抗原呈递,作为 T 细胞免疫治疗的更好靶点
- 批准号:
2885451 - 财政年份:2023
- 资助金额:
$ 8.01万 - 项目类别:
Studentship
Targeting immunoproteasome-mediated antigen presentation in colorectal cancer immunotherapy
结直肠癌免疫治疗中靶向免疫蛋白酶体介导的抗原呈递
- 批准号:
10385926 - 财政年份:2022
- 资助金额:
$ 8.01万 - 项目类别:
Lipid Antigen Presentation as a Driver of T2D Inflammation
脂质抗原呈递作为 T2D 炎症的驱动因素
- 批准号:
10509043 - 财政年份:2022
- 资助金额:
$ 8.01万 - 项目类别:
Enhancing antigen presentation in triple negative breast cancers through CD40 agonist, Flt3 ligand, and anthracycline chemotherapy
通过 CD40 激动剂、Flt3 配体和蒽环类化疗增强三阴性乳腺癌的抗原呈递
- 批准号:
10704008 - 财政年份:2022
- 资助金额:
$ 8.01万 - 项目类别:
Sex Differences in lipid antigen presentation, impact of lipid antigen presentation on peripheral lipid metabolism
脂质抗原呈递的性别差异,脂质抗原呈递对外周脂质代谢的影响
- 批准号:
10818273 - 财政年份:2022
- 资助金额:
$ 8.01万 - 项目类别:
Enhancing antigen presentation in triple negative breast cancers through CD40 agonist, Flt3 ligand, and anthracycline chemotherapy
通过 CD40 激动剂、Flt3 配体和蒽环类化疗增强三阴性乳腺癌的抗原呈递
- 批准号:
10349397 - 财政年份:2022
- 资助金额:
$ 8.01万 - 项目类别: