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Therapeutic Targeting of MIF in a Spondyloarthritis Mouse Model

Therapeutic Targeting of MIF in a Spondyloarthritis Mouse Model
MIF 在脊柱关节炎小鼠模型中的治疗靶向
批准号:
381460
负责人:
Haroon Nigil
金额:
$22.01万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2018
资助国家:
加拿大
项目状态:
已结题
起止时间:
2018-03-01 至 2021-03-01

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中文摘要
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英文摘要
Ankylosing spondylitis (AS) is the most severe form of spondyloarthritis (SpA) resulting in significant disability and increased mortality. Inflammation and fusion of the spine are the two most important features of this disease. The cause of AS is not we
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HIF1-alpha interacts with MIF to drive inflammation and new bone formation in spondyloarthritis
  • 批准号:
    445586
  • 项目类别:
    Operating Grants
  • 资助金额:
    $48.49万
  • 财政年份:
    2021
  • 负责人:
    Haroon Nigil
  • 依托单位:
Human Immunology Spondyloarthritis Team (HUMISPOT) studying immunopathogenesis, disease heterogeneity and drug discovery in spondyloarthritis
  • 批准号:
    395724
  • 项目类别:
    Operating Grants
  • 资助金额:
    $1.46万
  • 财政年份:
    2018
  • 负责人:
    Haroon Nigil
  • 依托单位:
Personalized medicine for ankylosing spondylitis
  • 批准号:
    365355
  • 项目类别:
    Operating Grants
  • 资助金额:
    $14.57万
  • 财政年份:
    2017
  • 负责人:
    Haroon Nigil
  • 依托单位:
Definitive treatment of AS by blocking Macrophage Migration Inhibitory Factor (MIF)
  • 批准号:
    351879
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.29万
  • 财政年份:
    2016
  • 负责人:
    Haroon Nigil
  • 依托单位:
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