Therapeutic Targeting of MIF in a Spondyloarthritis Mouse Model
Therapeutic Targeting of MIF in a Spondyloarthritis Mouse Model
批准号:
381460
负责人:
Haroon Nigil
金额:
$22.01万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2018
资助国家:
加拿大
项目状态:
已结题
起止时间:
2018-03-01 至 2021-03-01
中文摘要
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英文摘要
Ankylosing spondylitis (AS) is the most severe form of spondyloarthritis (SpA) resulting in significant disability and increased mortality. Inflammation and fusion of the spine are the two most important features of this disease. The cause of AS is not we
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会议论文
HIF1-alpha interacts with MIF to drive inflammation and new bone formation in spondyloarthritis
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批准号:445586
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项目类别:Operating Grants
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资助金额:$48.49万
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财政年份:2021
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负责人:Haroon Nigil
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依托单位:
Human Immunology Spondyloarthritis Team (HUMISPOT) studying immunopathogenesis, disease heterogeneity and drug discovery in spondyloarthritis
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批准号:395724
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项目类别:Operating Grants
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资助金额:$1.46万
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财政年份:2018
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负责人:Haroon Nigil
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依托单位:
Personalized medicine for ankylosing spondylitis
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批准号:365355
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项目类别:Operating Grants
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资助金额:$14.57万
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财政年份:2017
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负责人:Haroon Nigil
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依托单位:
Definitive treatment of AS by blocking Macrophage Migration Inhibitory Factor (MIF)
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批准号:351879
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项目类别:Operating Grants
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资助金额:$7.29万
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财政年份:2016
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负责人:Haroon Nigil
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依托单位:
Studies on the complex interaction of autophagy with endoplamic reticulum aminopeptidase 1, unfolded protein response and natural killer cell response in the pathogenesis of ankylosing spondylitis
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批准号:310329
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项目类别:Operating Grants
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资助金额:$7.29万
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财政年份:2014
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负责人:Haroon Nigil
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依托单位:
Immunogenetic influences on the clinical phenotype of Ankylosing Spondylitis
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批准号:194035
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项目类别:Fellowship Programs
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资助金额:$8.01万
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财政年份:2009
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负责人:Haroon Nigil
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依托单位:
Immunogenetic influences on the clinical phenotype of ankylosing spondylitis
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批准号:197231
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项目类别:Studentship Programs
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资助金额:$7.29万
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财政年份:2009
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负责人:Haroon Nigil
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依托单位:
海外基金