Structures and Reactions of New Main-Group Organometallic Compounds

该补助金是在有机和高分子化学 程序. 在这项研究中， 有机烃的活性锂或碱金属盐 阴离子的一系列标准有机镁试剂将 研究了 随着这些化学物质的平衡，一种新的 形成带负电荷的负碳离子， 增强化学反应性。 这种动态平衡还可以 通过加入冠醚或 络合剂螯合带正电荷的金属离子 导致明显不同的化学平衡。 具体而言，拟议的研究涉及 新型有机金属化合物的制备、结构和反应 主族金属的种类。 这项研究的主要部分 将涉及镁离子。 这些负有机镁 离子将由普通的有机化合物合成， 化合物的多种方式，包括添加配位 试剂，如冠醚和穴状配体，或简单的盐，如 如碱金属醇盐和四烷基卤化铵。 镁酸盐物种的结构和反应将是 研究了 镁离子一般是相当多 比常规有机镁化合物反应性更强， 一些基材提供不同的产品。 其他 有机镁物种的合成和研究 结构上包括有机镁阳离子（RMg+）， 二有机镁化合物（R2Mg），其通过 配位基团如冠醚。 的一部分 拟议的工作还将涉及制备新的有机金属 其他金属的种类，特别是由 有机铝或有机锌化合物与冠醚。

This grant is in the Organic and Macromolecular Chemistry Program. In this study the influence of the addition of highly reactive lithium or alkali metal salts of organic hydrocarbon anions to a series of standard organomagnesium reagents will be investigated. As these chemical species equilibrate, a new negatively charged carbanion is formed that exhibits greatly enhanced chemical reactivity. This dynamic equilibrium can also be favorably altered by the addition of crown ethers or complexing agents the sequester the positively charged metal ions resulting in markedly different chemical bahavior. Specifically, the proposed research is concerned with preparations, structures, and reactions of new organometallic species of main-group metals. A major portion of the research will concern magnesiate ions. These negative organomagnesium ions will be synthesized from ordinary organic compounds in a number of ways compounds, including addition of coordinating agents, such as crown ethers and cryptands, or simple salts, such as alkali metal alkoxides and tetraalkylammonium halides. Structures and reactions of magnesiate species will be investigated. Magnesiate ions generally are considerably more reactive than conventional organomagnesium compounds and with some substrates furnish different products. Other organomagnesium species to be synthesized and studied structurally include organomagnesium cations (RMg+) and diorganomagnesium compounds (R2Mg) that are stabilized by coordinating groups such as crown ethers. A portion of the proposed work also will involve preparation of new organometallic species of other metals, particularly species formed from organoaluminum or organozinc compounds with crown ethers.