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Analysis of the molecular mechanisms by which the MARCH1 E3-ubiquitin ligase regulates immune responses and tolerance.

Analysis of the molecular mechanisms by which the MARCH1 E3-ubiquitin ligase regulates immune responses and tolerance.
分析 MARCH1 E3-泛素连接酶调节免疫反应和耐受的分子机制。
批准号:
303785
负责人:
Thibodeau Jacques
金额:
$58.31万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2014
资助国家:
加拿大
项目状态:
已结题
起止时间:
2014-03-01 至 2019-03-01

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英文摘要
Our main objective is to understand the mechanism by which the body can terminate immune reactions against invaders so that chronic inflammation and autoimmune diseases do not ensue. IL-10 is a mediator that is secreted by immune cells and circulates in b
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MHC II antigen presentation: Modulation by E3-ubiquitin ligases of the MARCH family
  • 批准号:
    172135
  • 项目类别:
    Operating Grants
  • 资助金额:
    $36.27万
  • 财政年份:
    2008
  • 负责人:
    Thibodeau Jacques
  • 依托单位:
海外基金