Recombinant DNA Technology: A Core Research Facility

重组 DNA 技术：核心研究设施

• 批准号: 8703819
• 负责人: David Pearson
• 金额: --
• 依托单位: California State University-Los Angeles
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1987
• 资助国家: 美国
• 起止时间: 1987-08-01 至 1991-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8703819&HistoricalAwards=false
• 关键词: Recombinant; DNA; Technology; Core; Research

The Research Improvment in Minority Institutions (RIMI) program was established to provide support to strengthen the research environments and capabilities of predominantly minority institutions or institutions that have substantial minority student populations. Eligible institutions must also have graduate programs in science or programs in engineering. Funding is provided for faculty research in fields of science and engineering supported by the Foundation and for the acquisition of research instrumentation. California State University - Los Angeles will use RIMI support to establish a core research facility for recombinant DNA technology. The investigators will explore the regulation of neuroactive peptide production and release, the expression of action genes during development, the regulation of membrane development during the sporulation cycle of Bacillus subtilis, the structural definition of viral protein genes in mutant Sendai viruses, and the characterization of gram-negative anaerobes. Many experiments will utilize cDNA synthesis and molecular cloning techniques. The principal investigator is a well-trained biologist with a specialty in neuroendocrinology. He has published several articles in refereed journals. The Foundation has supported this project because more minorities will have opportunities to participate in meritorious research in recombinant DNA technology.

在少数民族机构（RIMI）计划的研究成果的建立，以提供支持，以加强研究环境和主要少数民族机构或机构的能力，有大量的少数民族学生群体。符合条件的机构还必须有科学或工程项目的研究生课程。基金会资助科学和工程领域的教师研究，并用于购买研究仪器。加州州立大学-洛杉矶将利用RIMI的支持建立重组DNA技术的核心研究设施。研究人员将探索神经活性肽产生和释放的调节，发育过程中作用基因的表达，枯草芽孢杆菌孢子形成周期中膜发育的调节，突变仙台病毒中病毒蛋白基因的结构定义以及革兰氏阴性厌氧菌的特征。许多实验将利用cDNA合成和分子克隆技术。主要研究者是一位训练有素的生物学家，具有神经内分泌学专业。他在权威期刊上发表了几篇文章。该基金会支持这一项目，因为更多的少数民族将有机会参与重组DNA技术的有益研究。