Teacher Enhancement in Molecular Biology and Recombinant DNA Technology

9454355 Bhattacharjee 由NSF支持的分子生物学和重组DNA技术教师增强研讨会的发起是为了向高中生物学教师提供所需的基本知识和熟练掌握分子生物学和重组DNA技术的最新进展。 该项目的目标是改善生物学的教学，吸引更多的学生从事生物医学科学的职业，并使俄亥俄州高中毕业生具备DNA知识。“这个夏季研讨会应该包括两周的密集讲座（主题包括DNA的结构和功能，原核和真核基因的基因组大小和性质，基因克隆和重组DNA技术的原理和应用），讨论，专题研讨会（主题包括致癌基因和职业，人类基因组计划，进化和植物生物技术），实地考察一家俄亥俄州生物技术公司，教案制定，以及涉及简单重组DNA技术的动手实验室实验（E.大肠杆菌转化、质粒DNA分离、重组DNA的限制性酶切和凝胶电泳分析）。 每次讲习班将挑选20名教师。 通过扩大外展工作，至少有一半的教师将积极从俄亥俄州的市中心高中招聘。 每位参与教师将获得津贴、旅费、住宿费和餐费，以及一本教科书、配件、录像带、俄亥俄州的资助机构和研究资源实验室名单、一个电泳凝胶盒和电源，以及各种实验室用品。 教学团队将包括PI，一名教师助理，其他迈阿密教师，研究生助教，高中硕士教师，课程和评估顾问。 为了增加该项目的影响，PI和教职员工将开展区域和年度总结性后续活动。 参与教师所属学校和地区的二级教师将参与后续活动。 由于这个项目，在目前的赠款期结束时，俄亥俄州100多所高中的1万多名学生将受益。

9454355 Bhattacharjee The Teacher Enhancement workshop in molecular biology and recombinant DNA technology supported by the NSF was initiated to provide high school biology teachers with needed basic knowledge and proficiency in recent advances of molecular biology and recombinant DNA technology. The objectives of the project are to improve the teaching of biology, attract more students to careers in biomedical sciences, and make Ohio high school graduates "DNA literate." This summer workshop should involve two weeks of intensive lectures (topics include structure and function of DNA, genome size and propoerties of prokaryotic and eukaryotic genes, and the principles and applications of gene cloning and recombinant DNA technology), discussions, special seminars (topics include oncogene and career, human genome project, evolution and plant biotechnology), field trip to an Ohio biotechnology company, lesson plan development, and hands-on laboratory experiments involving simple recombinant DNA techniques (E. coli transformation, plasmid DNA Isolation, restriction digestion and gel electrophoretic analysis of recombinant DNA). Twenty teachers would be selected for each workshop. Through expanded outreach efforts, at least half of the teachers will be actively recruited from the inner-city high schools of Ohio. Each participating teacher will be provided with a stipend, travel, room and meal expenses as well as a textbook, accessories, video tapes, a list of granting agencies and research resource laboratories in Ohio, an electrophoretic gel box and power supply, and various laboratory supplies. The instructional team would include the PI, one faculty associate, other Miami faculty, graduate teaching assistants, high school master teachers, curriculum and assessment consultants. In order to increase the impact of the project, the PI and the faculty associate would conduct regional and annual summative follow-up activities. Second-tier teachers from the sch ools and districts of the participating teachers will be included in the follow-up activities. As a result of this project, at the end of the current grant period more than 10,000 students in more than 100 high schools in Ohio woul be benefitted.